Decreased Incidence of Respiratory Infections in Children After Vaccination with Ten-valent Pneumococcal Vaccine

The Pediatric Infectious Disease Journal
Samuel SigurdssonÁsgeir Haraldsson

Abstract

Respiratory tract infections (RTIs) and antibiotic usage are common in children, increasing the risk of antibacterial resistance. The introduction of protein-conjugated pneumococcal vaccines has led to reduction in pneumococcal infections. In 2011, pneumococcal protein-conjugated vaccine-10 was introduced into the national childhood vaccination in Iceland, a population not earlier vaccinated against pneumococcus, with 95% vaccine uptake in the first year. The aim of the study was to evaluate the number of children visiting the Children's Hospital Iceland for RTIs before and after the introduction of the vaccine. Admissions and visits to the Children's Hospital because of RTIs were recorded, and children aged 3 months to 2 years in the nonvaccine eligible cohort (born 2008-2010) were compared with the vaccine eligible cohort (born in 2011). Statistical analysis was done using large sample Z test and incidence rate ratios (IRRs) were calculated. A significant reduction in incidence rate was found when comparing the nonvaccine eligible cohort with the vaccine eligible cohort, both for acute otitis media (AOM) (IRR: 0.76; 95% confidence interval: 0.67-0.87; P < 0.0001) and for pneumonia (IRR: 0.77; 95% confidence interval: 0.64-0.9...Continue Reading

References

Oct 27, 1999·JAMA : the Journal of the American Medical Association·D K ShayL J Anderson
Nov 27, 1999·FEMS Immunology and Medical Microbiology·J M HamentT F Wolfs
Feb 26, 2004·Paediatric Respiratory Reviews·Pearay L Ogra
May 25, 2005·Paediatric Respiratory Reviews·Talal Farha, Anne H Thomson
Jul 14, 2005·Scandinavian Journal of Infectious Diseases·Gunnar TomassonKarl G Kristinsson
Sep 28, 2006·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Vilhjalmur A ArasonKarl G Kristinsson
Mar 4, 2008·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael S Benninger
Dec 17, 2009·Acta Paediatrica·S KristjánssonG Wennergren
Apr 6, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ellen R Wald
Sep 21, 2011·The Journal of Infectious Diseases·Kirsty R ShortOdilia L Wijburg
Oct 25, 2011·BMC Pediatrics·Ruth B ThorntonPeter C Richmond
Jan 14, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D HervásJ A Hervás
Mar 17, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sylvia TaylorMark Haggard
Oct 17, 2012·Paediatric Respiratory Reviews·Sam Mehr, Nicholas Wood
Oct 27, 2012·The Pediatric Infectious Disease Journal·Shabir A MadhiJoanne Wolter
Nov 3, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Menno R van den BerghElisabeth A M Sanders
Dec 12, 2012·Scandinavian Journal of Infectious Diseases·Thorolfur GudnasonKarl G Kristinsson
Apr 12, 2013·Clinical Reviews in Allergy & Immunology·Andrea T BorchersLaurel J Gershwin
May 1, 2013·Emerging Infectious Diseases·Eliane Terezinha AfonsoAna Lucia Andrade
May 8, 2013·The Laryngoscope·Sameer AhmedNeil Bhattacharyya
Aug 13, 2013·The Pediatric Infectious Disease Journal·Kohei HasegawaCarlos A Camargo
Jul 11, 2014·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·A PierangeliP Bagnarelli
Aug 28, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Shalom Ben-ShimolRon Dagan
Dec 30, 2014·PloS One·Tanja TodbergPreben Homøe

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Citations

Jul 28, 2016·Human Vaccines & Immunotherapeutics·Lijoy VargheseBernard Hoet
Apr 1, 2018·Acta Paediatrica·Urban Johansson KostenniemiSven-Arne Silfverdal
Mar 24, 2018·The Pediatric Infectious Disease Journal·Ellen R Wald, Gregory P DeMuri
Jan 23, 2019·Acta Paediatrica·Elias EythorssonÁsgeir Haraldsson
Dec 27, 2019·The Pediatric Infectious Disease Journal·Paola MarchisioElena Chiappini
Jun 13, 2020·Canadian Journal of Public Health = Revue Canadienne De Santé Publique·Zhou ZhouPhilippe De Wals
Jun 16, 2017·Current Otorhinolaryngology Reports·Caroline Bergenfelz, Anders P Hakansson
May 11, 2018·Salud pública de México·José Luis Díaz-OrtegaMaría de Lourdes García-García
Aug 9, 2020·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Jakob HolstiegeJörg Bätzing
Aug 15, 2017·International Journal of Pediatric Otorhinolaryngology·Ivo VojtekBernard Hoet

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