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Decreased miRNA expression in Klinefelter syndrome

Scientific Reports

Dec 2, 2017

Laura CiminoAldo E Calogero

Abstract

The widelyvariable phenotypic spectrum and the different severity of symptoms in men with Klinefelter syndrome (KS) suggest a role for epigenetic mediators. Therefore, the aim of this study is to evaluate the possible involvement of miRNAs in the clinical manifestations of KS. To accomp...read more

Mentioned in this Paper

Study
MRNA Maturation
Mononuclear Cells
Immune System Diseases
RNA library
Peripheral Blood
Peripheral Blood Mononuclear Cells (Lab Test)
Receptor Down-Regulation
RNA, Small Temporal
Kallmann Syndrome
5
20
Paper Details
References
  • References32
  • Citations1
1234
  • References32
  • Citations1

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microRNA expression profile of peripheral blood mononuclear cells of Klinefelter syndrome

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Decreased miRNA expression in Klinefelter syndrome

Scientific Reports

Dec 2, 2017

Laura CiminoAldo E Calogero

PMID: 29192217

DOI: 10.1038/s41598-017-16892-3

Abstract

The widelyvariable phenotypic spectrum and the different severity of symptoms in men with Klinefelter syndrome (KS) suggest a role for epigenetic mediators. Therefore, the aim of this study is to evaluate the possible involvement of miRNAs in the clinical manifestations of KS. To accomp...read more

Mentioned in this Paper

Study
MRNA Maturation
Mononuclear Cells
Immune System Diseases
RNA library
Peripheral Blood
Peripheral Blood Mononuclear Cells (Lab Test)
Receptor Down-Regulation
RNA, Small Temporal
Kallmann Syndrome
5
20

Feeds With Similar Papers

Hormone-Related Cancers

This feed focuses on hormone-related cancers including cancer of the breast, endometrium, ovary, prostate, testis, thyroid, and bone, all of which share unique mechanisms of carcinogenesis. Here is the latest research.

Chromosomal Abnormalities

Chromosome abnormalities can be classified as either structural or numerical. Numerical abnormalities include duplications or deletion of a pair of chromosomes, such as Down Syndrome. Structural abnormalities include missing, extra or switched parts of a chromosome. Discover the latest research on chromosomal abnormalities here.

Related Papers

Experimental and Therapeutic Medicine

microRNA expression profile of peripheral blood mononuclear cells of Klinefelter syndrome

Experimental and Therapeutic MedicineDecember 12, 2012
Weiguo SuiYong Dai
Fertility and Sterility

Phenotypic differences in mosaic Klinefelter patients as compared with non-mosaic Klinefelter patients

Fertility and SterilityFebruary 8, 2014
Mary K SamplaskiKeith A Jarvi
Paper Details
References
  • References32
  • Citations1
1234
  • References32
  • Citations1

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