Decreased release of somatostatin into the portal vein following electrical vagal stimulation in the cat

Acta Physiologica Scandinavica
K Uvnäs-WallenstenC Johansson

Abstract

Electrical vagal stimulations were performed in anesthetized cats, in which the spleen and the intestine below the duodenum had been removed. The cats were provided with acute antral pouches which were perfused during the experiments. Insulin, glucagon, gastrin and somatostatin were measured in portal vein blood (consisting of blood from the stomach and the pancreas). The antral perfusates were analyzed for gastrin and somatostatin. Electrical vagal stimulation increased the release of insulin and glucagon into the portal vein. Gastrin was elevated in antral perfusates and portal vein blood, whereas somatostatin increased the antral perfusates, but was reduced in portal vein blood. We assume that antral somatotostatin, like gastrin, is released into the blood. The finding that portal vein somatostatin was decreased following vagal stimulation, indicates that the release of somatostatin from another large source of somatostatin, presumably the fundic region of the stomach or the pancreas, was decreased by vagal activation.

References

Jan 1, 1977·Acta Physiologica Scandinavica·K Uvnäs-WallenstenR Luft
Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·K Uvnäs-WallenstenB Uvnäs
Jan 1, 1975·The American Journal of Digestive Diseases·C L SmithK Buchanan
Dec 1, 1978·Acta Physiologica Scandinavica·J M LundbergS Said
Jan 1, 1979·Acta Radiologica: Diagnosis·S EfendićR Luft
Jun 1, 1978·Acta Endocrinologica·S Gustavsson, G Lundquist
Feb 1, 1978·Acta Physiologica Scandinavica·K Uvnäs-WallenstenR Luft
Mar 1, 1978·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·K Uvnäs-WallenstenR Luft
Sep 1, 1978·Metabolism: Clinical and Experimental·A ArimuraC Meyers
Mar 1, 1977·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·K Uvnäs-WallenstenR Luft
May 1, 1977·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·K Uvnäs-Wallensten, G Nilsson
Jul 1, 1977·Acta Physiologica Scandinavica·G Nilsson, K Uvnäs-Wallensten
Jan 1, 1976·Acta Physiologica Scandinavica·K Uvnäs-WallensteinG Nilsson
Oct 1, 1974·Endocrinology·A KanetoK Kosaka
Mar 1, 1973·Proceedings of the Society for Experimental Biology and Medicine·G LanciaultF P Brooks
Jun 1, 1969·The American Journal of the Medical Sciences·E Aguilar-ParadaR H Unger
Jun 1, 1971·Metabolism: Clinical and Experimental·S EfendicR Luft
Jul 1, 1967·Diabetes·L A FrohmanR Javid
Mar 1, 1967·Endocrinology·A KanetoK Nakao
Jul 1, 1963·The Biochemical Journal·C N HALES, P J RANDLE

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Citations

Mar 1, 1981·Diabetologia·K Uvnäs-Wallensten
Mar 1, 1989·Digestive Diseases and Sciences·M R Lucey, T Yamada
Jan 1, 1991·Acta paediatrica Scandinavica·A M WidströmK Uvnäs-Moberg
Jan 1, 1983·Acta Physiologica Scandinavica·K Uvnäs-Moberg, M Eriksson
Apr 1, 1984·Acta Physiologica Scandinavica·K Uvnäs-Moberg, L Wetterberg
May 1, 1984·Acta Physiologica Scandinavica·K Uvnäs-MobergA L Hulting
Jan 1, 1986·Scandinavian Journal of Gastroenterology. Supplement·V Schusdziarra, R Schmid
Jun 1, 1996·Scandinavian Journal of Gastroenterology·B QianM el-Salhy
Mar 1, 1981·Diabetologia·K Uvnäs-Wallensten
Jul 1, 1987·Acta paediatrica Scandinavica·G MarchiniK Uvnäs-Moberg
Feb 11, 1986·The American Journal of Physiology·B AhrénG J Taborsky
Dec 1, 1995·International Journal of Pancreatology : Official Journal of the International Association of Pancreatology·F C BrunicardiD K Andersen

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