Decreased trend in hospital mortality from pancreatic cancer despite increase in number of hospital admissions

PloS One
Sanjay BhandariNalini Guda

Abstract

Pancreatic cancer is one of the common cancers in US and is associated with high mortality and morbidity. The objectives of our study were to look at the recent trends in the number of hospitalizations with pancreatic cancer. We identified patients with a discharge diagnosis of pancreatic cancer in the National Inpatient Sample from 2007 to 2011 using International Classification of Diseases-Clinical Modification, 9th revision (ICD-9-CM) codes. We looked at the yearly trend in the hospitalizations with pancreatic cancer and the outcomes which included length of stay (LOS), hospital charges and in-hospital mortality. We also performed multivariate analysis to look for the predictors of mortality. There were 450, 414 patients with discharge diagnosis of pancreatic cancer. There was 18% increase in hospitalizations with pancreatic cancer in 2011 compared to 2007. Most of the patients were Caucasian (63%) with the mean age of 68 ± 0.14 years, had Medicare (57%) as primary insurance, were from Southern region (35%) and had higher Charlson Comorbidity Index (CCI) (87% with CCI > = 5). 6% underwent Whipple's procedure in the index hospitalization. After the adjustment for inflation, the mean hospital charges increased from $ 47,331 in...Continue Reading

References

Sep 22, 1998·Annals of Surgery·J A SosaJ L Cameron
Oct 15, 2003·Archives of Internal Medicine·Kathleen McDavidMichel P Coleman
Oct 20, 2006·Population Health Metrics·Catherine M MichaudChristopher J L Murray
Nov 23, 2006·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jordan M WinterCharles J Yeo
Sep 25, 2008·Cancer Control : Journal of the Moffitt Cancer Center·James F HelmMokenge P Malafa
May 1, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·June M McKoyCharles L Bennett
May 1, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Benjamin D SmithThomas A Buchholz
Jun 29, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S CascinuUNKNOWN ESMO Guidelines Working Group
Oct 10, 2014·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Aaron I Vinik
May 16, 2015·Biochimica Et Biophysica Acta·Divya SinghSharmila Shankar
Jan 9, 2016·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Feb 3, 2016·Lancet·Terumi KamisawaKyoichi Takaori
Jun 2, 2016·American Society of Clinical Oncology Educational Book·Lynn M Matrisian, Jordan D Berlin
Jun 3, 2016·CA: a Cancer Journal for Clinicians·Kimberly D MillerAhmedin Jemal
Sep 21, 2016·Best Practice & Research. Clinical Gastroenterology·Thomas B Brunner, Thomas Seufferlein

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Citations

Feb 9, 2021·World Journal of Gastrointestinal Surgery·Hassaan BariBobby V M Dasari

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