Decreasing profile of residual sulphaquinoxaline in eggs

British Poultry Science
N FurusawaH Yamaguchi

Abstract

1. Sulphaquinoxaline (SQ) was added to the diet of laying hens at 200 mg/kg for 7 successive days. Contents (mg/kg) of SQ in albumen and egg yolk of eggs laid after drug withdrawal were determined by high pressure liquid chromatography (HPLC). The contents in the whole egg were calculated taking into consideration the respective weights of albumen and egg yolk. 2. A time-lag in the initiation of decrease of SQ from eggs after the withdrawal of dietary SQ was observed. 3. The decreasing pattern from whole egg could be well described by the following equation with a time-lag of 1.0 d, y = 2.07 e-0.5620(t-1.0), where y is the SQ content in whole egg, t is time (d) after the withdrawal of dietary SQ and a constant of 2.07 is the SQ content in whole egg laid at the withdrawal. 4. Biological half-life of SQ in the whole egg was estimated to be 1.23 d. 5. From the above equation, SQ residue of whole egg laid at 9th d after withdrawal will be below the detection limit of 0.01 mg/kg.

References

May 1, 1977·Poultry Science·H OikawaK Katagiri
Aug 19, 1971·Biochimica Et Biophysica Acta·C I Osuoji
Dec 1, 1970·Nihon juigaku zasshi. The Japanese journal of veterinary science·T OnoderaY Oshima

Citations

Feb 24, 2001·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·N Furusawa
Aug 11, 1998·Zentralblatt für Veterinärmedizin. Reihe A·N FurusawaH Yamaguchi
Jan 15, 2016·Journal of Veterinary Pharmacology and Therapeutics·G J Schefferlie, P Hekman
Jun 18, 2011·Journal of Veterinary Pharmacology and Therapeutics·V GoettingL A Tell
Feb 24, 2015·Food Chemistry·Nina BilandžićŽeljko Cvetnić

Related Concepts

Animal Feed (Substance)
Microbicides
High Pressure Liquid Chromatography Procedure
Drug Residues
Egg Whites
Egg Yolk (Dietary)
Egg Food Product
Oviposition
Sulfaquinoxaline

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