Decreasing rates of Kaposi's sarcoma and non-Hodgkin's lymphoma in the era of potent combination anti-retroviral therapy

AIDS
Andrew E GrulichJohn M Kaldor

Abstract

To describe the changing incidence of Kaposi's sarcoma (KS) and non-Hodgkin's lymphoma (NHL) in people with HIV in Australia during the time period of introduction of potent combination anti-retroviral therapy. A national, population-based linkage study of cancer and HIV registration data. We calculated person-year rates of KS and NHL in people after reporting of HIV diagnosis. Trends in cancer incidence rates were examined, based on four time periods defined by the availability of specific anti-retroviral therapies. Linkage identified 206 cases of KS and 235 cases of NHL in 8108 people reported with HIV infection. There was an increasing trend in NHL incidence rates over the four time periods (P for trend, 0.012), but incidence for the period since the availability of the new therapies was significantly lower than that for the period immediately prior (incidence rate ratio 0.58; 95% confidence interval, 0.36-0.92). Incidence of KS had been decreasing prior to the new therapies and declined further since their widespread use (P for trend, 0.045). Population-based incidence rates of AIDS related KS and NHL have decreased since the widespread use of potent anti-retroviral therapies in Australia. NHL incidence decreased less than ...Continue Reading

Citations

Jun 24, 2009·Archives of Internal Medicine·Nancy Crum-CianfloneBrian K Agan
Jul 12, 2008·Cancer Causes & Control : CCC·Saira BahlLoraine D Marrett
Nov 23, 2013·Annales d'endocrinologie·Justine BonsHervé Lefebvre
Jul 11, 2003·Hematology/oncology Clinics of North America·Jamie H Von Roenn
Feb 8, 2003·The Lancet Oncology·Luigino Dal Maso, Silvia Franceschi
Nov 2, 2004·Nature Reviews. Cancer·Paolo MoniniBarbara Ensoli
Dec 16, 2005·Cell Research·Charles Wood, William Harrington
Jul 17, 2013·SAHARA J : Journal of Social Aspects of HIV/AIDS Research Alliance·Pride Linda
Jan 5, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Fabrice BonnetUNKNOWN Groupe d'Epidemiologie Clinique du SIDA en Aquitaine
Jun 28, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L Martín-CarboneroUNKNOWN Caelyx/Kaposi's Sarcoma Spanish Group
Sep 14, 2001·Current Opinion in Oncology·C A Clarke, S L Glaser
Sep 10, 2003·Current Opinion in Oncology·Ariela Noy
Oct 18, 2005·AIDS·Emanuela VaccherUNKNOWN Italian Cooperative Group on AIDS, Tumors (GICAT)
Aug 28, 2007·AIDS·Michael J SilverbergDonald I Abrams
Jun 4, 2008·AIDS·Emmanuelle Boffi El AmariUNKNOWN Swiss HIV Cohort Study
May 5, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Nancy F Crum-CianfloneScott Wegner
Nov 29, 2007·Journal of Clinical Pathology·K L GroggA Dogan
Jan 15, 2003·Annual Review of Medicine·David T Scadden
Apr 30, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Elizabeth Crabb BreenOtoniel Martinez-Maza
Dec 20, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Shehnaz K HussainOtoniel Martínez-Maza
Sep 10, 2005·Blood·Lindsay M MortonMartha S Linet
Jun 15, 2007·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Ann O'LearyChristine Galavotti
Apr 2, 2009·Haematologica·Mark BowerUNKNOWN UK CHIC Steering Committee
Mar 7, 2014·Infectious Agents and Cancer·Sally N Akarolo-AnthonyClement A Adebamowo
Jun 13, 2009·Future Oncology·Gary M Clifford, Silvia Franceschi
Mar 4, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Marcelo ChenYi-Ming Arthur Chen
Feb 14, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Chad J AchenbachUNKNOWN Centers for AIDS Research (CFAR) Network of Integrated Clinical Systems (CNICS)
Jun 29, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Nancy A HessolUNKNOWN WIHS Collaborative Study Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

AIDS Malignancies (ASM)

HIV infection increases the risk of non-communicable diseases common in the aged, including cardiovascular disease, neurocognitive decline, non-aids malignancies, osteoporosis, and frailty. Discover the latest research in AIDS malignancies.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

HIV/AIDS-Related Malignancies

HIV/AIDS infection increases the risk of non-communicable diseases common in the aged including HIV/AIDS-related malignancies. Discover the latest research in HIV/AIDS-related malignancies.

Related Papers

Journal of the National Cancer Institute
International Collaboration on HIV and Cancer
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
C S Rabkin
© 2021 Meta ULC. All rights reserved