Deep Brain Stimulation for Pain in the Modern Era: A Systematic Review

Neurosurgery
Leonardo A FrizonAndre G Machado

Abstract

Deep brain stimulation (DBS) has been considered for patients with intractable pain syndromes since the 1950s. Although there is substantial experience reported in the literature, the indications are contested, especially in the United States where it remains off-label. Historically, the sensory-discriminative pain pathways were targeted. More recently, modulation of the affective sphere of pain has emerged as a plausible alternative. To systematically review the literature from studies that used contemporary DBS technology. Our aim is to summarize the current evidence of this therapy. A systematic search was conducted in the MEDLINE, EMBASE, and Cochrane libraries through July 2017 to review all studies using the current DBS technology primarily for pain treatment. Study characteristics including patient demographics, surgical technique, outcomes, and complications were collected. Twenty-two articles were included in this review. In total, 228 patients were implanted with a definitive DBS system for pain. The most common targets used were periaqueductal/periventricular gray matter region, ventral posterior lateral/posterior medial thalamus, or both. Poststroke pain, phantom limb pain, and brachial plexus injury were the most c...Continue Reading

References

Aug 21, 1997·The New England Journal of Medicine·J LeLorierF Derderian
Sep 24, 1999·Pain·R Melzack
Apr 21, 2004·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Dipankar Nandi, Tipu Z Aziz
Apr 23, 2004·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·R J Coffey
Jun 1, 2005·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Richard G BittarTipu Z Aziz
Jul 5, 2005·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Richard G BittarTipu Z Aziz
Aug 13, 2005·European Journal of Pain : EJP·Harald BreivikDerek Gallacher
May 6, 2006·Cephalalgia : an International Journal of Headache·A L GreenT Z Aziz
Aug 15, 2006·Stereotactic and Functional Neurosurgery·Takamitsu YamamotoChikashi Fukaya
Jan 24, 2007·Lancet Neurology·Felipe FregniAlvaro Pascual-Leone
Mar 8, 2007·Neurosurgical Focus·Dirk RascheVolker M Tronnier
Aug 19, 2007·Acta Neurochirurgica. Supplement·S L F OwenT Z Aziz
Jul 22, 2009·PLoS Medicine·David MoherUNKNOWN PRISMA Group
Apr 1, 2004·Neuromodulation : Journal of the International Neuromodulation Society·Alexander L GreenTipu Z Aziz
Apr 1, 2006·Neuromodulation : Journal of the International Neuromodulation Society·Sarah L F OwenTipu Z Aziz
Oct 26, 2012·Neuromodulation : Journal of the International Neuromodulation Society·Andre G MachadoDonald A Malone
Nov 15, 2012·Neurosurgery·Sandra G J BoccardAlexander L Green
Aug 24, 2013·Stereotactic and Functional Neurosurgery·Stefan HunscheMohammad Maarouf
Dec 18, 2013·The Journal of Pain : Official Journal of the American Pain Society·Alan M GrayRichard B Scott
Feb 15, 2014·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Ralf BaronRod S Taylor
Jul 1, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Sandra G J BoccardTipu Z Aziz
Apr 6, 2017·Annals of Neurology·Scott F LempkaAndre G Machado
May 31, 2017·Neuromodulation : Journal of the International Neuromodulation Society·Hannah MaslenTipu Aziz
Jun 21, 2017·Neuromodulation : Journal of the International Neuromodulation Society·Vasco AbreuErlick A C Pereira

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Citations

Sep 25, 2019·Brain Sciences·Sarah Marie FarrellTipu Aziz
Feb 12, 2020·Neuromodulation : Journal of the International Neuromodulation Society·Sarasa TohyamaMojgan Hodaie
Mar 17, 2020·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Kevin Pacheco-BarriosFelipe Fregni
Aug 28, 2020·BMJ Case Reports·Timo Rafael Ten BrinkePepijn van den Munckhof
Feb 8, 2021·CNS Drugs·Hanwool Ryan ChoiMichael M Bottros
Apr 28, 2021·Scientific Reports·Charles W LuParag G Patil
Jun 3, 2021·Brain Sciences·David BergeronDang Khoa Nguyen
Aug 4, 2020·Neuromodulation : Journal of the International Neuromodulation Society·Stephen E JonesAndre G Machado
Jun 17, 2020·Operative Neurosurgery·Alon KashanianNader Pouratian

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