Deep brain stimulation for the treatment of Parkinson's disease: the experience of the Neurosurgical Department in Monza

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
A LandiS M Gaini

Abstract

deep brain stimulation is a widely accepted surgical therapy for the symptomatic treatment of advanced parkinson's disease; high frequency chronic stimulation of the subthalamic nucleus proved its efficacy to control the major motor symptoms. In the neurosurgical department of Monza we treated 72 parkinsonian patients (November 1998-January 2003). One year follow-up results are: decrease of tremor 90%, hypertonous 56%, bradykinesia 70%, voice impairment amelioration 30%, mean total daily L-dopa intake reduced 58%. Freezing and balance did not ameliorate, some voice impairment and psychic derangement have been observed. Major surgical complications were: haemorrage (1 case - transient hemiparesis), infections (2 cases), pulmonary embolisation (1 case). To optimise the surgical results, careful clinical and instrumental selection of the patients are mandatory before surgery.

Citations

Nov 8, 2013·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Aparna Wagle Shukla, Michael Scott Okun
Jun 15, 2007·Journal of the Neurological Sciences·Alan DiamondJoseph Jankovic
Sep 15, 2009·AJNR. American Journal of Neuroradiology·D DormontE Bardinet
Jul 1, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Valerie VoonAlexander I Tröster
Jul 1, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Anthony E LangValerie Voon
Jul 1, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Günther DeuschlValerie Voon
Aug 23, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Chul Hyoung LyooMyung Sik Lee

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