Deep Cerebral Venous Thrombosis Treatment : Endovascular Case using Aspiration and Review of the Various Treatment Modalities.

Clinical Neuroradiology
Leonard Ll YeoAnil Gopinathan

Abstract

Deep cerebral venous thrombosis (CVT) is an uncommon condition with a high morbidity and mortality. The optimal treatment approach for deep CVT remains uncertain and due to its low prevalence, randomized trials are not feasible. We showcase a straight sinus thrombosis treated with a large bore aspiration and performed a meta-analysis of the available literature to characterize and evaluate the various treatment modalities for patients with deep CVT. We conducted a systematic search in PubMed, EMBASE and Ovid Medline using appropriate keywords/MESH terms search strategy. All patients with thrombosis involving the deep venous sinuses were included if treatment records were available. Outcome measures included recanalization of the affected sinus, good functional outcome assessed by a modified Rankin scale (mRS) of 0-2 or reported independent functional outcomes, permanent neurological deficits, further hemorrhage and mortality. A total of 69 studies comprising 120 patients were included in the analysis. Anticoagulation was the most common treatment (85.8%), whilst local intrasinus thrombolysis was performed in 40.0% of the patients and mechanical endovascular modalities were employed in 20.0% of the patients. Recanalization of th...Continue Reading

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Citations

Dec 2, 2020·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Tian Ming TuLeonard Ll Yeo
Dec 12, 2020·Scientific Reports·Dagmar KrajíčkováMartin Vališ
Apr 25, 2021·Journal of the Neurological Sciences·Enrico FerranteFrancesco Allegrini
Jun 14, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Ashish K DubeyUsha K Misra
Aug 11, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Fatma Şimşek, Ravza Tosunoğlu

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