Abstract
The carotid intima-media thickness (cIMT) is an important biomarker for cardiovascular diseases and stroke monitoring. This study presents an intelligence-based, novel, robust, and clinically-strong strategy that uses a combination of deep-learning (DL) and machine-learning (ML) paradigms. A two-stage DL-based system (a class of AtheroEdge™ systems) was proposed for cIMT measurements. Stage I consisted of a convolution layer-based encoder for feature extraction and a fully convolutional network-based decoder for image segmentation. This stage generated the raw inner lumen borders and raw outer interadventitial borders. To smooth these borders, the DL system used a cascaded stage II that consisted of ML-based regression. The final outputs were the far wall lumen-intima (LI) and media-adventitia (MA) borders which were used for cIMT measurements. There were two sets of gold standards during the DL design, therefore two sets of DL systems (DL1 and DL2) were derived. A total of 396 B-mode ultrasound images of the right and left common carotid artery were used from 203 patients (Institutional Review Board approved, Toho University, Japan). For the test set, the cIMT error for the DL1 and DL2 systems with respect to the gold standard...Continue Reading
Citations
Jul 23, 2020·Angiology·Vijay ViswanathanJasjit S Suri
Sep 5, 2020·Ultrasonic Imaging·Nirvedh H MeshramTomy Varghese
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Feb 7, 2021·Medical & Biological Engineering & Computing·Mohit AgarwalJasjit S Suri
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Aug 10, 2020·Computers in Biology and Medicine·Mainak BiswasJasjit S Suri
Sep 13, 2020·Computers in Biology and Medicine·Jasjit S SuriSubbaram Naidu
Oct 17, 2020·Computers in Biology and Medicine·Ankush D JamthikarJasjit S Suri