Deep sedation in natural orifice transluminal endoscopic surgery (NOTES): a comparative study with dogs.

Surgical Endoscopy
Mohammad Al-HaddadLynetta J Freeman

Abstract

Natural orifice transluminal endoscopic surgery (NOTES) has been mostly performed with the animal under general and inhalational anesthesia (IA-NOTES). To date, NOTES using propofol sedation (PS-NOTES) has not been investigated. This study aimed to assess the feasibility and safety of PS-NOTES for transgastric oophorectomy with carbon dioxide insufflation and to compare its success rates with those of conventional IA-NOTES. In this prospective randomized study, NOTES oophorectomy was performed for 19 female dogs randomized to two conditions: PS (study group) and IA (control group). Sedation success rates (ability to visualize and resect ovaries without converting to IA), operative success rates (ability to resect and retrieve both ovaries in full using only NOTES), and vital parameters including hemodynamic and respiratory changes were documented. In the PS-NOTES group (n = 9), the sedation success rate was 100 %. The operative success rate was 67 % (6 of 9 animals) compared with 80 % (8 of 10 animals) in the IA-NOTES group. No purposeful movement occurred during surgical manipulation and no respiratory or cardiovascular complications in occurred the PS group. Heart rate (HR) and end-tidal carbon dioxide (ETCO(2)) were signific...Continue Reading

References

May 1, 1996·Acta Anaesthesiologica Scandinavica·E BuresL Lacoste
Apr 1, 1997·The British Journal of Surgery·D H WallaceP J O'Dwyer
Aug 8, 1998·The European Journal of Surgery = Acta Chirurgica·M S ChumillasV Viciano
Dec 2, 2004·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·M G TytherleighA Gordon
Sep 1, 2005·The American Journal of Gastroenterology·Andrea RiphausTill Wehrmann
Jan 13, 2006·Surgical Endoscopy·D RattnerUNKNOWN ASGE/SAGES Working Group
Oct 3, 2006·Surgical Innovation·Michael F McGeeJeffrey Ponsky
Apr 4, 2007·Surgical Endoscopy·Jeffrey M MarksMichael F McGee
Jan 8, 2008·Surgical Innovation·Ricardo ZorrónAndre Lacerda Oliveira
Nov 6, 2008·Gastrointestinal Endoscopy·David R LichtensteinJohn J Vargo
Mar 3, 2009·Gastrointestinal Endoscopy·Lynetta J FreemanPaul W Snyder
May 21, 2009·Paediatric Anaesthesia·Jerrold Lerman, Martin Jöhr
Jun 25, 2009·Gastroenterology·Douglas K RexNizam Meah
Dec 8, 2009·Gastrointestinal Endoscopy·John J VargoPaul Y Kwo
Dec 10, 2009·Surgical Endoscopy·Gustavo SalinasJeffrey M Marks

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Citations

Oct 24, 2014·World Journal of Gastroenterology : WJG·Jayashree Sood

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