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Defective lysosomal enzyme secretion in kidneys of Chediak-Higashi (beige) mice

The Journal of Cell Biology

Dec 1, 1975

E J BrandtR T Swank

PMID: 408

Abstract

The beige mouse is an animal model for the human Chediak-Higashi syndrome, a disease characterized by giant lysosomes in most cell types. In mice, treatment with androgenic hormones causes a 20-50-fold elevation in at least one kidney lysosomal enzyme, beta-glucuronidase. Beige mice tre...read more

Mentioned in this Paper

D-Amino Acid Dehydrogenase
Alcohol Oxidoreductases
Spleen
Succinate Dehydrogenase
Myocardium
Kidney
LYST
Exo-beta-D-Glucuronidase
Lysosomes
GUSB
Paper Details
References
  • References19
  • Citations71
12345...

Defective lysosomal enzyme secretion in kidneys of Chediak-Higashi (beige) mice

The Journal of Cell Biology

Dec 1, 1975

E J BrandtR T Swank

PMID: 408

DOI:

Abstract

The beige mouse is an animal model for the human Chediak-Higashi syndrome, a disease characterized by giant lysosomes in most cell types. In mice, treatment with androgenic hormones causes a 20-50-fold elevation in at least one kidney lysosomal enzyme, beta-glucuronidase. Beige mice tre...read more

Mentioned in this Paper

D-Amino Acid Dehydrogenase
Alcohol Oxidoreductases
Spleen
Succinate Dehydrogenase
Myocardium
Kidney
LYST
Exo-beta-D-Glucuronidase
Lysosomes
GUSB

Related Papers

Paper Details
References
  • References19
  • Citations71
12345...
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