Abstract
Defensive responses include an array of specific behaviors, including flight, freezing, risk assessment, and defensive threat/attack, that are elicited by unconditioned threat stimuli such as predators or predator odors. Some individual defensive behaviors are selectively responsive to drugs effective against generalized anxiety disorder or panic, providing a rationale for their use in investigation of compounds that may be useful in treating these disorders. In addition, defensive behaviors toward predators and some predator odors show rapid conditioning to contextual stimuli, whereas other predator odors do not, although they too elicit defensiveness. This pattern suggests that the ability of a predator odor to predict danger may be a determinant of the degree to which that odor supports aversive conditioning. Predators and predator odors are also increasingly used in studies of brain systems potentially related to emotionality. These factors indicate the need for selective, reliable, and convenient tests of defensiveness to predators and predator odors using rat and mouse subjects.
References
Jan 1, 1990·Psychopharmacology·D C BlanchardR J Rodgers
Mar 1, 1989·Journal of Comparative Psychology·R J Blanchard, D C Blanchard
Nov 1, 1996·Physiology & Behavior·G GriebelR J Blanchard
Feb 11, 1999·Pharmacology, Biochemistry, and Behavior·R A DielenbergI S McGregor
Dec 11, 1999·Psychopharmacology·I S McGregor, R A Dielenberg
Dec 23, 1999·Journal of Comparative Psychology·R A Dielenberg, I S McGregor
Apr 3, 2001·Brain Research·R A DielenbergI S McGregor
Jan 22, 2002·Neuroscience and Biobehavioral Reviews·R J BlanchardD C Blanchard
Jan 22, 2002·Neuroscience and Biobehavioral Reviews·R A Dielenberg, I S McGregor
Jan 26, 2002·Behavioural Brain Research·Iain S McGregorRobert A Dielenberg
Feb 26, 2003·European Journal of Pharmacology·D Caroline BlanchardRobert J Blanchard
Apr 24, 2003·Behavioral Neuroscience·D Caroline BlanchardRobert J Blanchard
Jul 5, 2003·Neuroscience Letters·D Caroline BlanchardRobert J Blanchard
May 12, 2004·Physiology & Behavior·Mu YangD Caroline Blanchard
Apr 13, 2005·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Joseph A CataniaStephen Shiboski
Citations
Oct 12, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Paul R BurghardtHuda Akil
Oct 1, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Y-Lan Boureau, Peter Dayan
May 26, 2011·PloS One·Rebecca NalloorAlmira Vazdarjanova
Feb 13, 2016·Frontiers in Behavioral Neuroscience·Aron M Henriques-Alves, Claudio M Queiroz
Mar 10, 2015·ELife·Prabhat S KunwarDavid J Anderson
Oct 4, 2014·Frontiers in Behavioral Neuroscience·Margaret G McCueChristopher K Cain
Jun 14, 2016·Journal of Neurogenetics·Eric J HorstickHarold A Burgess
Jun 14, 2017·ELife·Elizabeth RickenbacherMarta A Moita
Nov 28, 2013·The Journal of Laryngology and Otology·E E Hoskison
Jun 17, 2016·Nature Communications·Tamás FüzesiJaideep S Bains
Jul 12, 2013·Journal of Neuroendocrinology·K KentR I Wood
Sep 2, 2017·Behavioural Pharmacology·Juliana CavalliAntonio P Carobrez
Oct 31, 2020·Animal Cognition·Adam L CraneGrant E Brown
Sep 26, 2020·Frontiers in Zoology·Ian Nicholas BestChi-Chien Kuo
Jun 3, 2021·Brain Sciences·Stefan M Brudzynski