PMID: 7940572Jun 1, 1994Paper

Defensive roles for secondary metabolites from marine sponges and sponge-feeding nudibranchs

Toxicon : Official Journal of the International Society on Toxinology
P Proksch

Abstract

In the marine environment sponges (Porifera) constitute one of the most interesting sources of bioactive natural products. The high frequency of bioactive components in these primitive filter-feeders is interpreted as chemical defence of sponges against environmental stress factors such as predation, overgrowth by fouling organisms or competition for space. The highest incidence of toxic or deterrent sponge metabolites is consequently found in habitats such as coral reefs that are characterized by intense competition and feeding pressure due, for example, to carnivorous fish. Further support for the adaptive significance of sponge constituents is derived from the observation that sponges which are growing exposed are usually more toxic than those growing unexposed. Whereas the chemical defence of sponges seems to be highly effective against most species of fish, a group of shell-less gastropods, the nudibranchs, has specialized on sponges. While feeding on sponges the nudibranchs sequester the effective chemical armoury of their prey, which is subsequently employed for their own protection. Some nudibranchs, however, have become independent of this interspecific flow of natural products and are able to accumulate defensive comp...Continue Reading

References

Oct 1, 1993·Natural Product Reports·D J Faulkner
Jan 1, 1993·Journal of Natural Products·T F Molinski
Dec 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J B Jackson, L Buss
Mar 11, 1983·Science·G CiminoG Villani
Sep 13, 1974·Science·G J Bakus, G Green
Mar 1, 1992·Journal of Chemical Ecology·S C Bobzin, D J Faulkner

Citations

Feb 1, 1995·Journal of Chemical Ecology·S HesbacherP Proksch
Mar 19, 2005·Marine Biotechnology·Detmer SipkemaRene H Wijffels
Jun 9, 2006·Journal of Industrial Microbiology & Biotechnology·Guangyi Wang
Jun 22, 2002·Toxicon : Official Journal of the International Society on Toxinology·Yohandra R TorresManoel O de Moraes
Aug 16, 2003·Biomolecular Engineering·Tõnu ReintammMerike Kelve
Aug 16, 2003·Biomolecular Engineering·Wei ZhangQuan Yuan
Jul 28, 2012·Journal of Natural Products·Thushara DiyabalanageKirk R Gustafson
Nov 10, 2013·Journal of Natural Products·Sunan JaisamutAnuchit Plubrukarn
Mar 31, 2006·Natural Product Reports·Wickramasinghe M Bandaranayake
Nov 26, 2008·Natural Product Reports·Danielle Skropeta
Jul 6, 2006·Applied and Environmental Microbiology·Heinz C SchröderWerner E G Müller
Dec 25, 2007·Applied and Environmental Microbiology·Naglaa M MohamedRussell T Hill
Jan 26, 2010·Marine Drugs·Marieke KoopmansRene H Wijffels
Nov 11, 2011·Marine Drugs·Sean D StoweJohn Cavanagh
May 6, 2008·Investigational New Drugs·Mario Luiz Conte da FrotaJosé Cláudio Fonseca Moreira
May 30, 2014·Natural Product Reports·Danielle Skropeta, Liangqian Wei
Sep 16, 2005·Chemistry : a European Journal·Thomas P BradyEmmanuel A Theodorakis
Jan 24, 2015·Annales pharmaceutiques françaises·M El WahidiT Bamhaoud
Apr 20, 2011·International Journal of Biological Macromolecules·Ramjee PallelaVenkateswara Rao Janapala
Mar 9, 2018·Marine Drugs·Kasmiati KasmiatiMakoto Ojika
Nov 15, 2017·Natural Product Reports·Lewis J Dean, Michèle R Prinsep
Jan 28, 2017·MicrobiologyOpen·Anna Christensen, Glenroy D A Martin
Mar 26, 1998·Pharmazie in unserer Zeit·G König, A D Wright
Jul 12, 2017·Marine Biotechnology·Dennis VersluisDetmer Sipkema
Apr 11, 2019·Nature Communications·Daniel F R ClearyNicole J de Voogd

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