Defining Blanking Period Post-Pulmonary Vein Antrum Isolation

JACC. Clinical Electrophysiology
Pouria AlipourYaariv Khaykin

Abstract

This study sought to determine the exact period after pulmonary vein antrum isolation (PVI) during which early recurrence of atrial tachyarrhythmia (ERAT) does not predict late arrhythmia recurrence (LR), in order to better define the blanking period. Recurrence of atrial fibrillation after PVI is not uncommon. The first 3 months after PVI have been commonly treated as a blanking period, during which ERAT is not thought to predict LR after PVI; however, recent studies have shown that ERAT does predict LR. Baseline and follow-up data for 636 patients (mean age: 61.4 ± 10.6 years; 67.1% male; 59% paroxysmal atrial fibrillation; 31.4% ERAT) who underwent PVI between 2010 and 2014 were included. Recurrences were monitored by electrocardiography and Holter monitoring at 1-, 3-, 6-, 9-, and 12-month intervals post-procedure. Receiver-operating characteristic curve analysis was used to define the blanking period after PVI. Overall, 51%, 76%, and 92% of patients who had ERAT in the first, second, and third month post-PVI, respectively, also experienced LR (p = 0.001). Using a logistic regression model, those manifesting ERAT during the first, second, and third month post-PVI were 4.22, 9.03, and 19.43 (p = 0.001) times more likely to e...Continue Reading

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Citations

Jan 28, 2020·Journal of Cardiovascular Electrophysiology·Gesa von OlshausenFrieder Braunschweig
Jun 27, 2020·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·De-Yan YangQuan Fang
Sep 19, 2020·Journal of Cardiovascular Electrophysiology·Jin Hee ChoiKook Jin Chun
Oct 3, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Giuseppe StabileClaudio Tondo
Jun 15, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Christian SteinbergUNKNOWN CIRCA-DOSE Study Investigators
Sep 15, 2021·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Miruna A PopaFelix Bourier
Sep 28, 2021·The International Journal of Cardiovascular Imaging·Yanjuan ZhangMinglong Chen
Dec 25, 2021·Journal of Cardiovascular Electrophysiology·Dimitrios A VrachatisSpyridon Deftereos

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