Defining clusters of young autistic and typically developing children based on loudness-dependent auditory electrophysiological responses.

Molecular Autism
Patrick DwyerSusan M Rivera

Abstract

Autistic individuals exhibit atypical patterns of sensory processing that are known to be related to quality of life, but which are also highly heterogeneous. Previous investigations of this heterogeneity have ordinarily used questionnaires and have rarely investigated sensory processing in typical development (TD) alongside autism spectrum development (ASD). The present study used hierarchical clustering in a large sample to identify subgroups of young autistic and typically developing children based on the normalized global field power (GFP) of their event-related potentials (ERPs) to auditory stimuli of four different loudness intensities (50, 60, 70, 80 dB SPL): that is, based on an index of the relative strengths of their neural responses across these loudness conditions. Four clusters of participants were defined. Normalized GFP responses to sounds of different intensities differed strongly across clusters. There was considerable overlap in cluster assignments of autistic and typically developing participants, but autistic participants were more likely to display a pattern of relatively linear increases in response strength accompanied by a disproportionately strong response to 70 dB stimuli. Autistic participants display...Continue Reading

References

Jan 1, 1990·Brain Topography·W Skrandies
Jan 1, 1987·Electroencephalography and Clinical Neurophysiology·F PerrinJ F Echallier
Aug 1, 1984·Biological Psychology·J PrescottJ H Gruzelier
Nov 27, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·N BruneauC Barthélémy
Dec 10, 1999·Journal of Autism and Developmental Disorders·U RosenhallC Gillberg
Aug 22, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·T FrodlU Hegerl
Mar 19, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Curtis PontonManuel Don
Jun 6, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Rita CeponieneRisto Näätänen
Nov 25, 2003·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Nicole BruneauCatherine Barthélémy
Dec 25, 2004·Hearing Research·Stéphanie KhalfaLionel Collet
Mar 24, 2005·NeuroImage·Akaysha C TangChristopher J McKinney
Nov 30, 2005·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Sally J Rogers, Sally Ozonoff
Oct 4, 2006·Journal of Autism and Developmental Disorders·Susan R LeekamJudith Gould
Apr 18, 2007·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·Scott D Tomchek, Winnie Dunn
May 23, 2007·Journal of Neuroscience Methods·Eric Maris, Robert Oostenveld
Jul 13, 2007·Journal of Autism and Developmental Disorders·Michelle A DunnJudith Gravel
May 24, 2008·Journal of Child Psychology and Psychiatry, and Allied Disciplines·A Ben-SassonA S Carter
Aug 1, 2009·Journal of Autism and Developmental Disorders·Alison E LaneManya T Angley
Jan 15, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Hsieh Fushing, Michael P McAssey
Jan 22, 2011·Computational Intelligence and Neuroscience·Denis BrunetChristoph M Michel
Sep 22, 2011·Journal of Autism and Developmental Disorders·Shulamite A GreenAlice S Carter
Nov 30, 2011·Proceedings of the National Academy of Sciences of the United States of America·Christine Wu NordahlDavid G Amaral
Aug 2, 2012·Journal of Abnormal Child Psychology·Micah O MazurekLea Ann Lowery
Aug 28, 2012·Journal of Autism and Developmental Disorders·Richard S Smith, Jonathan Sharp
Sep 14, 2012·Frontiers in Human Neuroscience·Manish SaggarClifford D Saron
Sep 28, 2013·Journal of Autism and Developmental Disorders·Franc C L DonkersAysenil Belger
Mar 19, 2014·Autism Research : Official Journal of the International Society for Autism Research·Alison E LaneSomer L Bishop
Sep 16, 2014·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Valerie L ShaferMonica Wagner
Oct 2, 2014·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Akira IwanamiNobumasa Kato
Feb 11, 2015·Journal of Autism and Developmental Disorders·Benjamin WeismüllerUlrich Schall
May 16, 2015·Journal of Autism and Developmental Disorders·Lauren M LittleGrace T Baranek
Jul 3, 2015·Autism : the International Journal of Research and Practice·Lorcan KennyElizabeth Pellicano
Aug 6, 2015·International Journal of Pediatric Otorhinolaryngology·Ali A DaneshAdrien A Eshraghi
Sep 12, 2015·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·Scott D TomchekWinnie Dunn
Oct 2, 2015·Perception·Ashley E Robertson, R David R Simmons
Oct 19, 2016·Autism Research : Official Journal of the International Society for Autism Research·Mirko UljarevićSusan Leekam
Oct 19, 2016·Autism Research : Official Journal of the International Society for Autism Research·Debra S Karhson, Edward J Golob
May 3, 2016·Autism Research : Official Journal of the International Society for Autism Research·Karla K AusderauGrace T Baranek
May 10, 2016·NeuroImage. Clinical·Russell G PortTimothy P L Roberts
Jun 9, 2016·Autism Research : Official Journal of the International Society for Autism Research·Lauren E LiberoDavid G Amaral
Aug 23, 2016·Child: Care, Health and Development·L M LittleW Dunn
Dec 7, 2016·Journal of Autism and Developmental Disorders·Marie ElwinLars Kjellin
Mar 8, 2017·Autism Research : Official Journal of the International Society for Autism Research·Mirko UljarevićAlison Lane
Apr 4, 2017·Autism Research : Official Journal of the International Society for Autism Research·Brittany N HandAlison E Lane
Jun 24, 2017·Autism Research : Official Journal of the International Society for Autism Research·Chantal VlaskampNiels Bilenberg

❮ Previous
Next ❯

Citations

Nov 25, 2020·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Zachary J WilliamsTiffany G Woynaroski
Sep 10, 2021·Journal of Autism and Developmental Disorders·Patrick DwyerSusan M Rivera

❮ Previous
Next ❯

Software Mentioned

EASYCAP
Cartool
SMART
BESA

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.