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Defining Essential Enhancer for Pluripotent stem cells using Features Oriented CRISPR-Cas9 Screen

bioRxiv

Nov 12, 2019

Hao Fei WangYuin-Han Loh

Abstract

Cis Regulatory Elements (CREs) regulate the expression of the genes in their genomic neighborhoods and influence cellular processes such as cell-fate maintenance and differentiation. To date, there remain major gaps in the functional characterization of CREs and the identification of it...read more

Mentioned in this Paper

Regulation of Cell-cell Adhesion
Study
Cellular Process
Classification
Pluripotent Stem Cells
Genome
Genes
LIF
CRISPR-Cas Systems
Sequence Determinations, RNA
15
4
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Defining Essential Enhancer for Pluripotent stem cells using Features Oriented CRISPR-Cas9 Screen

bioRxiv

Nov 12, 2019

Hao Fei WangYuin-Han Loh

DOI: 10.1101/839316

Abstract

Cis Regulatory Elements (CREs) regulate the expression of the genes in their genomic neighborhoods and influence cellular processes such as cell-fate maintenance and differentiation. To date, there remain major gaps in the functional characterization of CREs and the identification of it...read more

Mentioned in this Paper

Regulation of Cell-cell Adhesion
Study
Cellular Process
Classification
Pluripotent Stem Cells
Genome
Genes
LIF
CRISPR-Cas Systems
Sequence Determinations, RNA
15
4

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