Defining prognostic factors in the elderly with community acquired pneumonia: a case controlled study of patients aged > or = 75 yrs

The European Respiratory Journal
W S Lim, J T Macfarlane

Abstract

Severity assessment in the elderly with community acquired pneumonia (CAP) may be different compared with younger patients. In particular, age per se may not be of prognostic significance in older patients. A case-control study in 158 patients aged > or = 75 yrs with CAP was conducted to determine the factors associated with in-hospital mortality. Cases were drawn from all patients aged > or = 75 yrs with CAP who died in 1997 in five hospitals in the mid-Trent region of the UK (Nottingham City Hospital, University Hospital Nottingham, Derby Royal Infirmary, Derby City General Hospital and Kings Hill Hospital). Controls were randomly selected from survivors also aged > or = 75 yrs. Factors associated with mortality were identified following a review of the medical casenotes and the contribution of these factors to mortality was determined using multivariate analysis. Absence of fever, tachycardia and chest radiograph features of bilateral involvement or an effusion were independently associated with mortality on multivariate analysis. The British Thoracic Society (BTS) severity rule was 50% sensitive and 64% specific in predicting death while the modified BTS rule displayed 67% sensitivity and 58% specificity. Age was not signif...Continue Reading

Citations

Feb 12, 2004·The Lancet Infectious Diseases·Jean-Paul Janssens, Karl-Heinz Krause
Oct 30, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mark Loeb
Nov 11, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·James D ChalmersAdam T Hill
Mar 24, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thuy LeJeremy Farrar
Jun 25, 2009·European Journal of Public Health·Puja R MylesTricia M McKeever
Apr 9, 2009·Respirology : Official Journal of the Asian Pacific Society of Respirology·Michael S Niederman
Oct 21, 2004·Drugs & Aging·Sridhar Neralla, Keith C Meyer
Jun 28, 2008·Drugs & Aging·Félix Gutiérrez, Mar Masiá
May 27, 2010·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Ivanka DjordjevićZorica Cirić
Apr 4, 2009·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Christiana van de NadortTheo J M Verheij
Dec 15, 2010·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Naomi StantonChris C Butler
Aug 3, 2012·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Jie DongYing Xu
Oct 31, 2006·The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists·David R Guay
Aug 18, 2006·Journal of the American Geriatrics Society·Tateaki NaitoHirotoshi Nakamura
Aug 26, 2014·PloS One·Florian F GrossmannChristian H Nickel
May 9, 2003·Clinics in Geriatric Medicine·Michael S Niederman, Qanta A A Ahmed
Jan 18, 2006·Respiratory Medicine·Ewoudt M W van de GardeHubert G M Leufkens
May 28, 2005·Expert Review of Anti-infective Therapy·Mark Loeb
Nov 10, 2006·Médecine et maladies infectieuses·K Faure
Aug 29, 2014·Therapeutic Advances in Infectious Disease·Antonella F SimonettiJordi Carratalà
Apr 8, 2010·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Timothy F Platts-MillsCharles B Cairns
Apr 1, 2008·Expert Review of Respiratory Medicine·Kirsty Buising
Feb 10, 2016·Current Opinion in Pulmonary Medicine·Michael T Bender, Michael S Niederman
Aug 7, 2007·Wiener klinische Wochenschrift·Christoph Wenisch

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