Defining regions of interest using cross-frequency coupling in extratemporal lobe epilepsy patients

Journal of Neural Engineering
Mirna GuirgisBerj L Bardakjian

Abstract

Clinicians identify seizure onset zones (SOZs) for resection in an attempt to localize the epileptogenic zone (EZ), which is the cortical tissue that is indispensible for seizure generation. An automated system is proposed to objectively localize this EZ by identifying regions of interest (ROIs). Intracranial electroencephalogram recordings were obtained from seven patients presenting with extratemporal lobe epilepsy and the interaction between neuronal rhythms in the form of phase-amplitude coupling was investigated. Modulation of the amplitude of high frequency oscillations (HFOs) by the phase of low frequency oscillations was measured by computing the modulation index (MI). Delta- (0.5-4 Hz) and theta- (4-8 Hz) modulation of HFOs (30-450 Hz) were examined across the channels of a 64-electrode subdural grid. Surrogate analysis was performed and false discovery rates were computed to determine the significance of the modulation observed. Mean MI values were subjected to eigenvalue decomposition (EVD) and channels defining the ROIs were selected based on the components of the eigenvector corresponding to the largest eigenvalue. ROIs were compared to the SOZs identified by two independent neurologists. Global coherence values we...Continue Reading

References

May 15, 1992·Science·G BuzsákiK Wise
Jun 1, 1990·Electroencephalography and Clinical Neurophysiology·D Panet-Raymond, J Gotman
May 1, 1995·Obstetrics and Gynecology·K YlinenT Laatikainen
Sep 23, 2000·Epilepsia·B Diehl, H O Lüders
Aug 28, 2001·Brain : a Journal of Neurology·F Rosenow, H Lüders
Dec 12, 2001·Neurology·N FoldvaryH Lüders
Sep 8, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Guido NolteMark Hallett
Dec 14, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Bart VanrumsteGrant J Carroll
Apr 2, 2005·Nature Reviews. Neuroscience·Alfons Schnitzler, Joachim Gross
Jul 7, 2007·Brain : a Journal of Neurology·Zsófia ClemensJan Born
Jul 13, 2007·Brain : a Journal of Neurology·Elena UrrestarazuJean Gotman
Feb 22, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Hiroshi OtsuboElizabeth J Donner
Apr 12, 2008·NeuroImage·Andrew C N ChenPeipei Wang
May 20, 2008·Lancet Neurology·Susan Spencer, Linda Huh
Dec 6, 2008·Epilepsia·Jerome EngelIstvan Mody
Jul 1, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·H KhamisS Simpson
Feb 26, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·B ClemensK Hollódy
May 14, 2010·Journal of Neurophysiology·Adriano B L TortNancy Kopell
Jan 18, 2011·Neurobiology of Disease·Maxime LévesqueMassimo Avoli
Feb 1, 2011·Epilepsy & Behavior : E&B·Francesco Brigo
Mar 1, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Hisaji ImamuraAkio Ikeda
Sep 9, 2011·Brain : a Journal of Neurology·Maryse A van 't KloosterGeertjan J M Huiskamp
Jan 19, 2012·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·C Alvarado-RojasM Le Van Quyen
Mar 17, 2012·Progress in Neurobiology·John G R JefferysFernando H Lopes da Silva
Mar 21, 2012·Human Brain Mapping·Luca BonfiglioMaria Chiara Carboncini
Apr 7, 2012·Progress in Neurobiology·J JacobsJ Gotman
Aug 3, 2012·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Pradeep N ModurSong Zhang
Oct 2, 2012·Progress in Neurobiology·Adriano B L TortJurij Brankačk
Jun 19, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Federico MelaniJean Gotman
Nov 12, 2013·Experimental Neurology·George M IbrahimSam M Doesburg
Dec 26, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Karolin KerberJulia Jacobs
Jan 23, 2014·Journal of Neuroscience Methods·Dino Dvorak, André A Fenton

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Citations

May 15, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Yutaka NonodaEishi Asano
Aug 19, 2016·Frontiers in Human Neuroscience·Mina AmiriJean Gotman
Dec 3, 2016·Journal of Neural Engineering·Sinisa ColicBerj L Bardakjian
Feb 10, 2018·Scientific Reports·Chien-Hung Yeh, Wenbin Shi
Oct 1, 2019·Annals of Neurology·Haiteng JiangBin He
Aug 28, 2020·Neuroinformatics·Gabriela J JurkiewiczJarosław Żygierewicz
Jun 18, 2017·Epilepsia·Maeike ZijlmansMichel Le Van Quyen
Sep 14, 2017·The Journal of Physiology·Atul MaheshwariJeffrey L Noebels
Feb 12, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Stefan RamppRoland Coras
Dec 31, 2020·Brain Communications·Vasily GrigorovskyBerj L Bardakjian
Oct 16, 2020·International Journal of Molecular Sciences·Mark S AquilinoPeter L Carlen
Aug 19, 2021·Brain Connectivity·Jeffrey R TenneyDarren S Kadis

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