Defining the tipping point: a complex cellular life/death balance in corals in response to stress.

Scientific Reports
Tracy D AinsworthWilliam Leggat

Abstract

Apoptotic cell death has been implicated in coral bleaching but the molecules involved and the mechanisms by which apoptosis is regulated are only now being identified. In contrast the mechanisms underlying apoptosis in higher animals are relatively well understood. To better understand the response of corals to thermal stress, the expression of coral homologs of six key regulators of apoptosis was studied in Acropora aspera under conditions simulating those of a mass bleaching event. Significant changes in expression were detected between the daily minimum and maximum temperatures. Maximum daily temperatures from as low as 3°C below the bleaching threshold resulted in significant changes in both pro- and anti-apoptotic gene expression. The results suggest that the control of apoptosis is highly complex in this eukaryote-eukaryote endosymbiosis and that apoptotic cell death cascades potentially play key roles tipping the cellular life/death balance during environmental stress prior to the onset of coral bleaching.

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Citations

Jan 9, 2013·Proceedings of the National Academy of Sciences of the United States of America·Daniel J BarshisStephen R Palumbi
Apr 30, 2013·PloS One·Noelia Estévez-CalvarBeatriz Novoa
Oct 6, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Jianqiong YangLonghuo Wu
Jan 27, 2015·Frontiers in Cellular and Infection Microbiology·Janelle R ThompsonMónica Medina
Dec 26, 2013·G3 : Genes - Genomes - Genetics·Erik M LehnertJohn R Pringle
Apr 16, 2016·Science·Tracy D AinsworthWilliam Leggat
Dec 12, 2018·PeerJ·Eric Jordán-DahlgrenRosa E Rodríguez-Martínez

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Methods Mentioned

BETA
environmental stress

Software Mentioned

REST

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis