Definition of fields margins for palliative radiotherapy of pancreatic carcinoma

Molecular and Clinical Oncology
Milly BuwengeAlessio G Morganti

Abstract

The present study aimed to provide practical guidelines for palliative treatment of advanced carcinoma of the pancreas (CAP) with the 2D technique. Fifteen patients with locally advanced CAP consecutively treated with radiation therapy at the Radiation Oncology Center, Research and Care Foundation 'Giovanni Paolo II' (Campobasso, Italy) underwent computed tomography simulation in supine position. Definition of the clinical target volume (CTV) included the head and body of the pancreas, and the retropancreatic space. The planning target volume was defined by adding a margin of 14 mm to the CTV in the cranio-caudal direction and of 11 mm in radial direction. For each patient, 3 treatment plans were calculated using a cobalt source, 6 MV photons and 15 MV photons (box technique). Beams were drawn using the primary collimators without using multileaf collimators, and progressively optimized in order to respect the minimum dose (Dmin>90%) constraint. Once the final plan was achieved, distances of the fields edges from a set of reference points (bony or duodenal landmarks) were measured. Using this technique, 15 anterior-posterior and postero-anterior (AP-PA) beams and 15 pairs of lateral-lateral (LL) beams were defined for the diffe...Continue Reading

References

Apr 27, 2007·World Journal of Surgical Oncology·Ines GockelTheodor Junginger
Aug 12, 2009·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·V SharmaB Jeremic
Mar 5, 2010·International Journal of Radiation Oncology, Biology, Physics·Søren M BentzenEllen D Yorke
Apr 20, 2010·International Journal of Radiation Oncology, Biology, Physics·Susannah YovinoWilliam F Regine
May 28, 2010·The British Journal of Radiology·Y-C SongP Wang

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