PMID: 7542142Apr 1, 1995Paper

Definition of local recurrence after surgery for rectal carcinoma

The British Journal of Surgery
P J MarshP F Schofield

Abstract

Local recurrence rates of rectal carcinoma have been analysed among 284 patients in a prospective randomized multicentre trial of adjuvant preoperative radiotherapy for locally advanced rectal carcinoma. Wide variations in local recurrence rates are demonstrated depending on the definition of local recurrence employed and the subgroup studied. Thus after surgical operation alone, rates as high as 43.3 per cent or as low as 12.7 per cent can be calculated. After both adjuvant preoperative radiotherapy and operation the overall local recurrence rate is 12.8 per cent, although the local recurrence rate inside the radiotherapy field (true recurrence) may be as low as 2.3 per cent. It is recommended that local recurrence after operation for rectal carcinoma be defined as any detectable local disease at follow-up, occurring either alone or in conjunction with generalized recurrence, in patients who have undergone resection. A rate should be given both for all patients and for those operated on for cure, but not for the latter group alone as this could introduce bias.

References

Mar 1, 1991·The British Journal of Surgery·A R DixonJ T Holmes
Jan 1, 1988·Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer·R D James
Aug 23, 1986·British Medical Journal·P F SchofieldD E Tweedle
Sep 1, 1985·The British Journal of Surgery·W Duncan
Jan 1, 1984·The British Journal of Surgery·R K PhillipsL P Fielding
Jan 1, 1984·The British Journal of Surgery·R K PhillipsL P Fielding
Mar 1, 1984·The British Journal of Surgery·J M GilbertA E Kark
Feb 20, 1993·Lancet·J K MacFarlaneR J Heald
Feb 20, 1993·Lancet·L P Fielding
Jan 1, 1994·The British Journal of Surgery·A M Abulafi, N S Williams
Jul 6, 1963·British Medical Journal·B C MorsonH J Bussey

❮ Previous
Next ❯

Citations

May 2, 2001·Diseases of the Colon and Rectum·M KillingbackO F Dent
Jun 9, 2005·International Journal of Colorectal Disease·Jeffrey J MorkenCharles O Finne
May 24, 2011·International Journal of Colorectal Disease·Sigmar StelznerHelmut Witzigmann
Apr 30, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E Kapiteijn, C J H van de Velde
Feb 25, 2005·Annals of Surgery·Eric RullierFrank Zerbib
Apr 17, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·I R DanielsB J Moran
Jan 30, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·H K SigurdssonUNKNOWN Norwegian Colorectal Cancer Group
Apr 13, 2011·World Journal of Gastroenterology : WJG·Jose M Enríquez-NavascuésLuis Bujanda
Oct 13, 2011·World Journal of Gastroenterology : WJG·Renato CostiCesare Bordi
Jan 17, 2013·World Journal of Gastroenterology : WJG·Jun ZhaoJin Gu
Apr 30, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·W H SteupC J H van de Velde
Jul 13, 2014·International Journal of Radiation Oncology, Biology, Physics·Ane L AppeltAnders Jakobsen
Aug 3, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A J DebesM B Jacobsen
Jul 26, 2005·Clinical Radiology·P L TanN R Moore
Jan 1, 2003·The Surgical Clinics of North America·E Kapiteijn, C J H van de Velde
May 6, 1998·American Journal of Surgery·M Huguier, S Houry
Aug 27, 2013·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G RamsayM Loudon
Apr 25, 2000·The Australian and New Zealand Journal of Surgery·W H Isbister
Jul 7, 1999·The Australian and New Zealand Journal of Surgery·W H Isbister
Apr 20, 2007·The Cochrane Database of Systematic Reviews·R K S WongA Figueredo
Oct 5, 2018·The Cochrane Database of Systematic Reviews·Iosief AbrahaVincenzo Valentini
Apr 1, 1997·The British Journal of Surgery·E RullierM Parneix
Jan 17, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·O F DentE L Bokey
Feb 10, 2006·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A Radcliffe
Nov 29, 2017·Annals of the Royal College of Surgeons of England·S R MoosviJ Hernon
Sep 25, 2008·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·H H WasmuthO Røkke
Jan 1, 1996·The British Journal of Surgery·R J Nicholls, C Hall
Oct 22, 2020·Cancers·Ioannis KoliarakisJohn Tsiaoussis
Mar 7, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Caterina FoppaAntonino Spinelli
Jan 7, 2021·American Journal of Physiology. Gastrointestinal and Liver Physiology·Roy HajjarManuela M Santos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.