Definition, prevalence, clinical relevance and treatment of T-shaped uterus: systematic review.
To summarize in a systematic review the current evidence regarding definitions, diagnosis, prevalence, etiology, clinical relevance and impact of surgical treatment for T-shaped uterus not related to diethylstilbestrol (DES) exposure, and to highlight areas on which future research should focus. A search of PubMed, Scopus and EMBASE was performed on 9 April 2020 using the search terms 't-shaped OR t-shape OR infantile OR (lateral indentation) OR (diethylstilbestrol OR DES) AND (uterus OR uterine OR uteri) AND (anomaly OR anomalies OR malformation OR malformations)'. Additionally, the reference lists of the included studies were searched manually for other relevant publications. All studies presenting data on T-shaped uterus not associated with DES exposure and including at least 10 women were considered eligible. Studies regarding DES-related T-shaped uterus were excluded because DES has not been used since 1971. There were no restrictions on language, date of publication or status of publication. Of 2504 records identified by the electronic search, 20 studies were included in the systematic review. The majority of studies were of poor quality. In 11 of 16 studies reporting on the diagnosis of T-shaped uterus, the diagnostic me...Continue Reading
Diethylstilbestrol-induced müllerian abnormalities, septate uterus, genital tuberculosis and twin pregnancy with term delivery after in-vitro fertilization
Are implantation and pregnancy outcome impaired in diethylstilbestrol-exposed women after in vitro fertilization and embryo transfer?
Abnormalities of the uterus and cervix after diethylstilbestrol exposure: correlation of findings on MR and hysterosalpingography
Teratogenic effects of clomiphene, tamoxifen, and diethylstilbestrol on the developing human female genital tract
In utero exposure to diethylstilbestrol: adverse effects on the reproductive tract and reproductive performance and male and female offspring
Reproductive significance of changes in the endometrial cavity associated with exposure in utero to diethylstilbestrol
Upper genital tract changes and pregnancy outcome in offspring exposed in utero to diethylstilbestrol
Hysteroscopic metroplasty in the diethylstilbestrol-exposed uterus and similar nonfusion anomalies: effects on subsequent reproductive performance; a preliminary report
Endometrial pattern in diethylstilboestrol-exposed women undergoing in-vitro fertilization may be the most significant predictor of pregnancy outcome
Hysteroscopic metroplasty in diethylstilboestrol-exposed and hypoplastic uterus: a report on 24 cases
Reproductive performance after hysteroscopic metroplasty in the hypoplastic uterus: a study of 29 cases
Endometrial receptivity is preserved in Diethylstilbestrol-associated and other Müllerian anomalies: evidence from tubal embryo transfer
Three-dimensional ultrasound in the diagnosis of Müllerian duct anomalies and concordance with magnetic resonance imaging
Term delivery rate after hysteroscopic metroplasty in patients with recurrent spontaneous abortion and T-shaped, arcuate and septate uterus
Prevalence of uterine anomalies and their impact on early pregnancy in women conceiving after assisted reproduction treatment
The prevalence of congenital uterine anomalies in unselected and high-risk populations: a systematic review
Effect of prior birth and miscarriage frequency on the prevalence of acquired and congenital uterine anomalies in women with recurrent miscarriage: a cross-sectional study
Salpingotomy versus salpingectomy in women with tubal pregnancy (ESEP study): an open-label, multicentre, randomised controlled trial
Comparison of the ESHRE-ESGE and ASRM classifications of Müllerian duct anomalies in everyday practice
Accuracy of three-dimensional ultrasound compared with magnetic resonance imaging in diagnosis of Müllerian duct anomalies using ESHRE-ESGE consensus on the classification of congenital anomalies of the female genital tract
Intra- and inter-observer variability of uterine measurements with three-dimensional ultrasound and implications for clinical practice
Uterine cavity imaging, volume estimation and quantification of degree of deformity using automatic volume calculation: description of technique
Adenomyosis in infertile women: prevalence and the role of 3D ultrasound as a marker of severity of the disease
Dysmorphic Uterine Congenital Anomalies: A New Lateral Angle and a Cavity Width Ratio on 3D Ultrasound Coronal Section to Define Uterine Morphology
Classification of Uterine Anomalies by 3-Dimensional Ultrasonography Using ESHRE/ESGE Criteria: Interobserver Variability
Congenital Uterine Malformation by Experts (CUME): better criteria for distinguishing between normal/arcuate and septate uterus?
Outcome of assisted reproduction in women with congenital uterine anomalies: a prospective observational study
Hysteroscopic Corrections for Complete Septate and T-Shaped Uteri Have Similar Surgical and Reproductive Outcome
Are 3D ultrasound and office hysteroscopy useful for the assessment of uterine cavity after late foetal loss?
ESHRE/ESGE female genital tract anomalies classification system-the potential impact of discarding arcuate uterus on clinical practice
Hysteroscopic enlargement metroplasty for T-shaped uterus: 24 years' experience at the Strasbourg Medico-Surgical and Obstetrical Centre (CMCO)
Reproductive outcomes of office hysteroscopic metroplasty in women with unexplained infertility with dysmorphic uterus
Three-dimensional scan of the uterine cavity of infertile women before assisted reproductive technology use
Surgical correction of T-shaped uteri in women with reproductive failure: Long term anatomical and reproductive outcomes
Three-dimensional ultrasound in the diagnosis and the classification of congenital uterine anomalies using the ESHRE/ESGE classification: a diagnostic accuracy study
Long-Term Reproductive Outcomes after Hysteroscopic Treatment of Dysmorphic Uteri in Women with Reproductive Failure: An European Multicenter Study
Three-dimensional ultrasound diagnosis of T-shaped uterus is associated with adverse pregnancy outcomes after embryo transfer
Hysteroscopic outpatient metroplasty for T-shaped uterus in women with reproductive failure: Results from a large prospective cohort study
Impact of Hysteroscopic Metroplasty on Reproductive Outcomes of Women with a Dysmorphic Uterus and Recurrent Miscarriages: A Systematic Review and Meta-Analysis
Reply: T-shaped and dysmorphic uterus - misclassifications and low-quality evidence promote unnecessary surgery.
Reply: T-shaped uterus after oral contraception - considering myometrial contractions, endometrial volume and 3D saline contrast sonohysterography in diagnosis.
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