Definitive-intent radiotherapy for sinonasal carcinoma in cats: A multicenter retrospective assessment.

Veterinary and Comparative Oncology
Katerina StiborovaCarla Rohrer Bley

Abstract

Treatment of epithelial sinonasal tumours in cats is not commonly reported. In the newer reports, palliative radiation protocols have been described more often than definitive-intent protocols. In this multi-institutional retrospective study, we included 27 cats treated with single-modality radiotherapy. Cats were irradiated using 10 daily fractions of 4.2 Gy. Three cats (11.1%) experienced a complete clinical response and 17 (63%) had a partial clinical response. Stable clinical disease was noted in three cats (11.1%). Four cats (14.8%) showed progression within 3 months following treatment. The median time to progression for all cases was 269 days (95 % confidence intervals [CI]: 225; 314). The proportion of cats free of progression at 1 and 2 years was 24% (95% CI: 22%; 26%) and 5% (95% CI: 5%; 6%), respectively. None of the prognostic factors evaluated were predictive of outcome (anaemia, tumour volume at the time of staging, modified Adams stage, intracranial involvement, facial deformity, epistaxis, inappetence or weight loss). Median overall survival (OS) for all deaths was 452 days (95% CI: 334; 571). The proportion of cats alive at 1 and 2 years was 57% (95% CI: 37%; 77%) and 27% (95% CI: 25%; 29%), respectively. Surpr...Continue Reading

References

Jan 11, 1975·The Veterinary Record·T H DuckworthA F Julian
Oct 15, 1998·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·W M AdamsE G MacEwen
Oct 16, 1999·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·T A LaDueD E Thrall
Oct 27, 2001·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·T LadueUNKNOWN Veterinary Radiation Therapy Oncology Group
May 25, 2002·Journal of Feline Medicine and Surgery·R J MellanbyJ M Dobson
May 29, 2002·Animal Genetics·S A McCoardJ J Ford
Jul 22, 2004·Journal of Feline Medicine and Surgery·S M HendersonT J Gruffydd-Jones
Aug 3, 2006·Journal of the American Veterinary Medical Association·Kenneth M RassnickOrna Kristal
Aug 19, 2007·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Gabriella SfiligoiMichael S Kent
Nov 3, 2007·Journal of the American Animal Hospital Association·Katia Marioni-HenryKathleen B Muravnick
Jun 11, 2009·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·William M AdamsThomas C Havighurst
Oct 27, 2010·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Jessica A LawrenceMinesh P Mehta
Nov 19, 2011·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Michele A KeyerleberMatthew Podgorsak
Nov 26, 2013·The Veterinary Clinics of North America. Small Animal Practice·Nicki Reed
Jan 28, 2017·CA: a Cancer Journal for Clinicians·William M LydiattJatin P Shah

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Citations

Mar 5, 2021·Journal of Veterinary Internal Medicine·Hiroto YoshikawaMichael W Nolan

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