Degradation of N-acetyl tryptophan by low-energy (<12 eV) electrons

Journal of the American Chemical Society
H Abdoul-CarimeE Illenberger

Abstract

Secondary low-energy electrons are abundantly created during the early moments following the deposition of energy by radiation into cells. Here we show the ability of slow (<12 eV) electrons to effectively decompose gas-phase N-acetyl tryptophan (NAT) which can model a simple protein. The fragmentation of NAT, initiated via a resonant electron-molecule interaction exclusively at the peptide bridge, produces a large variety of negative species. The present findings contribute to the molecular description of the initial step in the radiation-induced damage.

References

Sep 3, 1970·The Journal of Physical Chemistry·M D Sevilla
Jul 18, 2001·Journal of the American Chemical Society·H Abdoul-CarimeL Sanche
Jan 10, 2002·Chemical Reviews·Jonathan C Rienstra-KiracofeG Barney Ellison
Aug 3, 2002·Oncogene·Keith D Robertson
Oct 19, 2002·Radiation Research·Jintana MeesungnoenSamlee Mankhetkorn
Jun 6, 2003·Physical Review Letters·G HanelT D Märk

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Citations

Jun 3, 2010·The Journal of Chemical Physics·J Kopyra, H Abdoul-Carime
May 9, 2014·The Journal of Chemical Physics·B F MinaevV A Minaeva
Dec 1, 2007·Journal of the American Chemical Society·Yury V Vasil'evMax L Deinzer
Mar 6, 2018·Physical Chemistry Chemical Physics : PCCP·Janina KopyraHassan Abdoul-Carime
Apr 20, 2006·Journal of the American Chemical Society·Yury V Vasil'evMax L Deinzer

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