DEGRO guidelines for the radiotherapy of non-malignant disorders : part III: hyperproliferative disorders

Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
M Heinrich SeegenschmiedtGerman Cooperative Group on Radiotherapy of Benign Diseases (GCG-BD)

Abstract

Radiation therapy (RT) is an established and effective treatment modality in the management of a large variety of hyperproliferative disorders and benign neoplasms. Objective of this article is to summarize the updated DEGRO consensus S2e guideline recommendations. This report comprises an overview of the relevant aspects of the updated guidelines with regard to treatment decision, dose prescription, and RT technique for a selected group of disorders including Morbus Dupuytren (MD)/Morbus Ledderhose (ML), keloids, Peyronie's disease (induratio penis plastica, IPP), desmoid tumors, pigmented villonodular synovitis (PVNS), symptomatic vertebral hemangiomas (sVH), and Gorham-Stout syndrome (GSS). On the basis of results in the literature, we attempted to classify the level of evidence (LoE) and the grade of recommendation (GR) according to the Oxford criteria. There is comprehensive evidence in the literature that RT is a reasonable and effective treatment modality for the treatment of all the above-mentioned disorders. The LoE varies from 2c to 4, and GR varies from A to C. The use of RT can be recommended for the interdisciplinary management of most of the reported disorders. It can be used in the primary treatment approach and ...Continue Reading

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Citations

Sep 25, 2015·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Khaled ElsayadHans Theodor Eich
Nov 9, 2016·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Christian T DietzelDirk Vordermark
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Jul 15, 2021·International Journal of Radiation Biology·Seyed Alireza JavadiniaRachna Kapoor

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