PMID: 8594004Nov 1, 1995Paper

Dehydration reduces cardiac output and increases systemic and cutaneous vascular resistance during exercise

Journal of Applied Physiology
J González-AlonsoE F Coyle

Abstract

This investigation determined the manner in which the cardiovascular system copes with the dehydration-induced reductions in cardiac output (Q) during prolonged exercise in the heat. On two separate occasions, seven endurance-trained subjects (maximal O2 consumption 4.70 +/- 0.41 l/min) cycled in the heat (35 degrees C) for 2 h, beginning at 62 +/- 2% maximal O2 consumption. During exercise, they randomly received either 0.2 liter of fluid and became dehydrated by 4.9 +/- 0.2% of their body weight [i.e., dehydration trial (DE)] or 3.6 +/- 0.4 liter of fluid and replaced 95% of fluid losses [i.e., euhydration trial (EU)]. During the 10- to 120-min period of EU, Q, mean arterial pressure (MAP), systemic vascular resistance (SVR), cutaneous vascular resistance (CVR), and plasma catecholamines did not change while esophageal temperature stabilized at 38.0 +/- 0.1 degrees C. Conversely, after 120 min of DE, Q and MAP were reduced 18 +/- 3 and 5 +/- 2%, respectively, compared with EU (P < 0.05). This was associated with a significantly higher SVR (17 +/- 6%) and plasma norepinephrine concentration (50 +/- 19%, P < 0.05). In addition, CVR was also significantly higher (126 +/- 16 vs. 102 +/- 6% of 20-min value; P < 0.05) during DE des...Continue Reading

Citations

Nov 24, 1998·The Journal of Physiology·J González-AlonsoB Nielsen
Feb 5, 2000·Journal of Applied Physiology·R G FritzscheE F Coyle
May 8, 2001·Exercise and Sport Sciences Reviews·E F Coyle, J González-Alonso
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Jan 5, 2013·European Journal of Applied Physiology·James PearsonJosé González-Alonso
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Aug 1, 2013·Medicine and Science in Sports and Exercise·Rochus PokanPeter Hofmann
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Nov 5, 2019·Frontiers in Nutrition·Adam D SealStavros A Kavouras
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