Dehydroepiandrosterone sulfate in a long-term care aged population

Gerontology
S LegrainE E Baulieu

Abstract

Ninety-four institutionalized subjects (mean age 82.9 years; 13 men and 81 women) were assessed for serum dehydroepiandrosterone sulfate (DHEAS) levels. The mean value was 457 ng/ml (SD = 426) in this cross-sectional study. There was a significant decrease in DHEAS levels with age. There was no difference among demented patients with Alzheimer's disease (n = 46), other dementia cases (n = 16), and other individuals (n = 32). The subjects treated for arterial hypertension had significantly lower DHEAS levels. No correlation was found between DHEAS and cortisol values. After age adjustment, no association was observed between DHEAS and chronic diseases, medications, several biochemical or hematological parameters, or 3-year mortality.

Citations

May 1, 1997·Journal of Psychiatric Research·R Rupprecht
Feb 12, 1998·Trends in Pharmacological Sciences·S Bastianetto, R Quirion
Aug 11, 1999·Trends in Neurosciences·R Rupprecht, F Holsboer
Oct 17, 2003·Drugs & Aging·Sylvie Legrain, Laurence Girard
Mar 24, 2005·Treatments in Endocrinology·Deborah R Cameron, Glenn D Braunstein
Nov 10, 2000·Aging : Clinical and Experimental Research·M H KähönenM Härkönen
Aug 20, 2011·European Journal of Endocrinology·Giovanni CoronaMario Maggi
Oct 16, 2010·Psychosomatic Medicine·Michael C GadingerJoachim E Fischer
Jul 1, 1997·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·T J Connelly, A P Kowalcyk
May 25, 2013·Stroke; a Journal of Cerebral Circulation·Monik C JiménezKathryn M Rexrode
May 8, 2002·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Brenda BreuerBarnett Zumoff
Oct 30, 1998·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·M F MorrisonT TenHave
Dec 10, 2008·Frontiers in Neuroendocrinology·Nicole ManingerSynthia H Mellon
Feb 5, 2008·Maturitas·Stéphanie NouveauOlivier de Lacharriere
Oct 2, 2007·Comptes rendus biologies·Olfa ChehabKacem Mahdouani
Sep 16, 2006·International Journal of Geriatric Psychiatry·Mario BoMario Molaschi
Dec 8, 2011·Journal of Neuroendocrinology·Y Dong, P Zheng
Aug 19, 2008·Journal of Psychiatric Research·Cornelius SchüleRainer Rupprecht
Jun 21, 2006·Contemporary Clinical Trials·Denise von MühlenElizabeth Barrett-Connor
Dec 29, 2012·Biochemical Pharmacology·Jean-Pierre SavineauEric Dumas de la Roque
May 7, 1999·Journal of Geriatric Psychiatry and Neurology·B R Ott, N J Owens
Oct 13, 1998·The Journal of Clinical Endocrinology and Metabolism·S KalmijnS W Lamberts
Feb 10, 1999·Experimental Gerontology·S S Yen, G A Laughlin

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