Delandin, a chitinase-like protein with antifungal, HIV-1 reverse transcriptase inhibitory and mitogenic activities from the rice bean Delandia umbellata

Protein Expression and Purification
X Y Ye, T B Ng

Abstract

An antifungal protein with a chitinase-like N-terminal sequence, designated delandin, was isolated from the rice bean. The protein exhibited a molecular weight of 28 kDa and was adsorbed on both blue Affi-Gel and SP-Toyopearl. It exerted antifungal action toward Mycosphaerella arachidicola, Botrytis cinerea, Fu- sarium oxysporum, Rhizoctonia solani, and Colletotrichum gossypii and inhibited the activity of human immunodeficiency virus 1 reverse transcriptase. The protein inhibited translation in rabbit reticulocyte lysate with a low potency. It elicited a mitogenic response from mouse splenocytes.

References

Feb 19, 1986·Biochimica Et Biophysica Acta·W K Roberts, C P Selitrennikoff
Nov 15, 1973·Journal of Molecular Biology·U K Laemmli, M Favre
Dec 21, 1993·Biochimica Et Biophysica Acta·L BarbieriF Stirpe
Jan 1, 1996·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·H X WangS T Chang
Jun 4, 1998·Biochemical and Biophysical Research Communications·B N JoshiP K Ranjekar
Mar 1, 2000·Biochemical and Biophysical Research Communications·X Y YeT B Ng
Jul 13, 2000·Biochemical and Biophysical Research Communications·X Y Ye, T B Ng
May 29, 2003·Journal of Insect Physiology·M A. AndersonR L. Heath

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Citations

Oct 16, 2004·The Journal of Peptide Research : Official Journal of the American Peptide Society·P H K Ngai, T B Ng
Aug 15, 2003·Journal of Peptide Science : an Official Publication of the European Peptide Society·Patrick H K Ngai, T B Ng
Sep 11, 2008·Journal of Food Science·S Y WangP F Rao
Mar 16, 2005·Protein Expression and Purification·Shaoyun WangXiuyun Ye
Mar 3, 2015·Proteomics·Pooja KesariPravindra Kumar
May 12, 2006·Peptides·Jack Ho WongTzi Bun Ng
Jun 10, 2010·Applied Microbiology and Biotechnology·Jack H WongF Liu
Sep 15, 2005·Phytotherapy Research : PTR·Kaleab AsresSimon Gibbons
Jun 24, 2009·Applied Microbiology and Biotechnology·Shaoyun WangPingfan Rao
May 6, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ramandeep KaurDinesh Kumar
Mar 5, 2004·Journal of Peptide Science : an Official Publication of the European Peptide Society·T B Ng, Patrick H K Ngai
Sep 2, 2011·Brazilian Journal of Biology = Revista Brasleira De Biologia·P G PraxedesR A B Pessoni
Aug 30, 2005·Biochemical and Biophysical Research Communications·Hexiang Wang, Tzi Bun Ng

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An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.