Delay in Treatment After Cancer Diagnosis in Adolescents and Young Adults: Does Facility Transfer Matter?

Journal of Adolescent and Young Adult Oncology
Jin MouRebecca H Johnson

Abstract

Background: Timeliness is one of the fundamental yet understudied quality metrics of cancer care. Little is known about cancer treatment delay among adolescent and young adult (AYA) cancer patients. This study assessed cancer treatment delay, with a specific focus on facility transfer and diagnosis/treatment interval. Methods: Based on MultiCare Health System's (MHS's) institutional cancer registry data of AYA patients diagnosed during 2006-2015, this study analyzed patient demographics, insurance, clinical characteristics, and time of diagnosis and treatment initiation. Chi-squared tests, cumulative hazard estimates, and Cox proportional regression were used for univariable analysis. Multivariate regression models were used to test the association between care transfer and days of interval or prolonged delay, controlling for baseline parameters. Results: Of 840 analytic AYA cases identified, 457 (54.5%) were both diagnosed and treated within MHS. A total of 45.5% were either diagnosed or treated elsewhere. Mean and median intervals for treatment initiation were 27.03 (95% CI = 21.94-33.14) and 8.00 days (95% CI = 5.00-11.00), respectively, with significant differences between patients with and without facility transfer. T...Continue Reading

References

Nov 1, 1991·The Journal of Pediatrics·B H PollockT J Vietti
Jun 1, 1993·Archives of Disease in Childhood·V SahaG MacKinlay
Apr 21, 1999·Lancet·A S Coates
Oct 27, 2001·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·H Bozcuk, C Martin
Mar 22, 2002·The Lancet Oncology·R Hollis, S Morgan
Feb 1, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jenny HuangWilliam J Mackillop
Aug 24, 2004·Health Economics·Anirban BasuJohn Mullahy
Jan 26, 2007·Cancer Treatment Reviews·Andrea Ferrari, Archie Bleyer
Jul 7, 2007·Pediatric Hematology and Oncology·Archie Bleyer
Jul 13, 2007·CA: a Cancer Journal for Clinicians·Archie Bleyer
Aug 4, 2007·The Oncologist·Sean MartinArchie Bleyer
Jan 10, 2008·Annals of Surgical Oncology·Karl Y BilimoriaClifford Y Ko
May 6, 2008·Pediatric Blood & Cancer·Tam Dang-TanEduardo L Franco
Sep 16, 2009·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Jeffrey T YorioDavid E Gerber
Aug 25, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David M ThomasAndrea Ferrari
Sep 22, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Brad ZebrackUNKNOWN LIVESTRONG Young Adult Alliance
Jan 29, 2011·Journal of Cancer Survivorship : Research and Practice·Linda C HarlanUNKNOWN AYA HOPE Study Collaborative Group
Apr 9, 2011·Annals of Surgery·Karl Y BilimoriaDavid J Bentrem
Jun 7, 2011·JAMA : the Journal of the American Medical Association·James J BiagiChristopher M Booth
Oct 20, 2011·Journal of Health Services Research & Policy·Fiona WalterJon Emery
Jun 16, 2012·CA: a Cancer Journal for Clinicians·Rebecca SiegelElizabeth Ward
Mar 5, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Marie Louise TørringPeter Vedsted
Jan 1, 2014·Journal of Adolescent and Young Adult Oncology·Rebecca H Johnson
Apr 29, 2014·Oncology Nursing Forum·Lisa Carter-HarrisSusan M Rawl
Jun 4, 2014·CA: a Cancer Journal for Clinicians·Carol E DeSantisAhmedin Jemal
Sep 18, 2014·Acta Haematologica·Mathew R Meeneghan, William A Wood
Feb 6, 2016·Cancer·Theresa H M KeeganUNKNOWN National Cancer Institute Next Steps for Adolescent and Young Adult Oncology Epidemiology Working Group
May 4, 2016·Journal of the National Cancer Institute·Xuesong HanAhmedin Jemal
Jun 3, 2016·CA: a Cancer Journal for Clinicians·Kimberly D MillerAhmedin Jemal
Oct 16, 2018·Journal of the National Cancer Institute·Lihua LiuDennis Deapen

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