Delay of growth and development in children with bronchial asthma, atopic dermatitis and allergic rhinitis

Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association
W F BaumE Klöditz

Abstract

The elevated incidence of short stature (body height < (-)x - 2s), skeletal retardation and delayed puberty in children with bronchial asthma or atopic dermatitis is generally attributed to the severity of the disorder. However, a series of findings indicate a causal influence of the atopy and the existence of atopic skeletal retardation per se.The observation that children with atopic disorders, whether bronchial asthma, atopic dermatitis or allergic rhinitis, exhibit a rate of short stature that is twice to five times higher than normal indicates atopic and thus genetically determined influences. The elevated prevalence of short stature associated with allergic rhinitis is especially significant, as this disorder cannot be included among the severe chronic disorders. The fact that skeletal retardation is more prevalent in boys than in girls by a ratio of about 2:1 and that a significantly more marked retardation of bone maturation is found in atopic in comparisons with non-atopic asthmatics also lend support to this postulation. The clinical relevance of atopic growth retardation is also supported by the close interaction of pathophysiological basal mechanisms of bone metabolism and the atopy status. Thus the local growth fac...Continue Reading

Citations

Jan 5, 2007·Indian Journal of Pediatrics·N F IsmailC J H Kelnar
Sep 30, 2003·The Journal of Allergy and Clinical Immunology·David B AllenStanley J Szefler
Feb 27, 2013·Respiratory Physiology & Neurobiology·Wioleta UmławskaDorota Sands
Oct 17, 2007·The Psychiatric Clinics of North America·Susan Turkel, Maryland Pao
Dec 7, 2007·Allergy·L B BacharierUNKNOWN European Pediatric Asthma Group
Mar 16, 2007·Journal of Clinical Periodontology·Peter MeiselThomas Kocher
Jul 25, 2007·Clinical Endocrinology·R J PerryS F Ahmed
Jul 24, 2012·Evidence-based Child Health : a Cochrane Review Journal·Michelle FoisyHywel C Williams
Jan 24, 2014·International Journal of Endocrinology·Tamara SvobodováJan Lebl
Oct 29, 2013·Archives of Disease in Childhood·Andrew Bush
Jul 6, 2015·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·G PouesselA Deschildre
Nov 18, 2003·Clinical and Experimental Dermatology·W K Woo, K E McKenna
Jan 20, 2015·The Cochrane Database of Systematic Reviews·Helen NankervisThomas Platts-Mills
Feb 12, 2015·Nutrition Research and Practice·Youngshin HanKyunghee Song
Feb 7, 2008·The Cochrane Database of Systematic Reviews·F Bath-HextallH C Williams
Feb 18, 2012·The Cochrane Database of Systematic Reviews·Fiona J Bath-HextallHywel C Williams
Oct 10, 2008·The Cochrane Database of Systematic Reviews·Robert John BoyleMimi Lk Tang
Sep 1, 2012·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Damir ErcegMirjana Turkalj

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