PMID: 1202168Oct 1, 1975Paper

Delayed decrement of the nerve impulse propagation during induced limb ischaemia in chronic hepatic failure

Journal of Neurology, Neurosurgery, and Psychiatry
V K Nielsen, T Kardel

Abstract

Sensory thresholds for vibrations and electrical shocks and the sensory nerve conduction velocity (median nerve) were measured during 30 minutes of induced limb ischaemia in 10 normal subjects and 15 patients with chronic hepatic failure. Sensory action potentials were recorded simultaneously at the wrist and elbow. Seven patients (group A) had a normal perception time for vibrations. As in normal subjects, the potential amplitude decreased from the onset of ischaemia, more pronounced at the elbow than at the wrist, and the conduction velocity became reduced more rapidly in the wrist-elbow than the first digit-wrist segment, indicating impulse propagation with decrement. Eight patients (group B) had a markedly prolonged perception time for vibrations. The reduction of potential amplitude and conduction velocity was considerably delayed, and the impulse propagation showed no evidence of decrement for 20-25 minutes of ischaemia. A rise of the threshold for electrical shocks was absent or very delayed. As in the two other groups, the rise was abrupt and occurred at the moment when the potential below the occluding cuff (elbow) was extinct. In both groups of patients there was an increasing temporal dispersion of action potentials ...Continue Reading

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Citations

Oct 1, 1988·Diabetologia·E A MassonA J Boulton
Oct 1, 1989·Journal of the Neurological Sciences·G J Parry, H Kohzu
Dec 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·D E PriceJ K Wales
Apr 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·T López-AlburquerqueJ de Portugal Alvarez
Jan 5, 1999·American Journal of Respiratory and Critical Care Medicine·P MayerP Lévy
Sep 1, 1986·Diabetes Research and Clinical Practice·N KuriyaS Nagataki
Oct 1, 1994·Diabetes Research and Clinical Practice·P LindströmA A Sima
Apr 1, 1985·The American Journal of Physiology·P A LowS Brimijoin

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