Delayed Effect of Active Pressure Treatment on Endolymphatic Hydrops

Audiology & Neuro-otology
Edoardo CovelliMaurizio Barbara

Abstract

To identify eventual correlations between the effect of low-pressure treatment and endolymphatic hydrops in Ménière patients. The study group consisted of subjects affected by definite Ménière disease (2015) and a severe degree of disability, who received a ventilation tube with or without a low-pressure treatment before undergoing a surgical procedure (vestibular neurectomy). After the placement of the ventilation tube, the subjects were either left alone with the tube or received 1 month of self-administered low-pressure therapy with a portable device. In all subjects, an electrocochleography (ECochG) was performed and specific questionnaires - Dizziness Handicap Inventory (DHI) and Functional Scale Level (FSL) - were completed before starting either arm of treatment, at the end of treatment, and then 3 and 6 months later. All selected subjects presented with an ECochG pattern that was indicative of endolymphatic hydrops before starting either treatment. At the end of pressure treatment, 80% showed symptomatic improvement while maintaining the hydropic ECochG pattern. At the 3-month control stage, the hydropic pattern resulted normalized (<0.5) in all the improved subjects. Although 1 month of low-pressure treatment provided ...Continue Reading

References

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Citations

Feb 28, 2019·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Louise DevantierHenriette Edemann-Callesen
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Feb 13, 2020·Frontiers in Neurology·Louise DevantierTherese Ovesen

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