Delayed Effects of Transcutaneous Organophosphate Poisoning in Four Children

Child Neurology Open
Milen PavlovicAsma A Al-Tawari

Abstract

Contamination or transcutaneous absorption of organophosphates (OP) is rare and there exist only few reports of such manner of poisoning. We report four children from the same family in whom temporal proximity of the disease onset, a detailed interrogation of parents and exclusion of other clinical differentials, led to the diagnosis of transcutaneous intoxication with organophosphates (diazinon). The contamination occurred during the game with a freshly used poison can. Uncommon clinical picture was marked by delayed signs predominantly reflecting certain nicotinic effects (muscle weakness, cramps) along with subtle neuropathic features occurring throughout a few weeks after initial event. Our illustrative cases can further contribute to the better awareness and understanding of variable spectrum of transcutaneous route of OP poisoning.

References

Aug 1, 1985·Neuropediatrics·E S RoachM R Lawless
Sep 1, 1987·Southern Medical Journal·A Halle, D D Sloas
Sep 1, 1971·Archives of Environmental Health·H I MaibachW F Serat
May 29, 2003·Current Drug Targets. CNS and Neurological Disorders·Milan JokanovicMelita Kosanovic
Oct 7, 2004·Journal of Toxicology. Clinical Toxicology·J G DahlgrenM Zwass
Jun 17, 2008·Annals of Emergency Medicine·G Randall BondUNKNOWN WHO EMRO Pediatric Insecticide Study Group
Dec 2, 2010·Indian Journal of Occupational and Environmental Medicine·S K RastogiD Ravishanker
Sep 3, 2011·Journal of Emergencies, Trauma, and Shock·Yair SadakaMatitiahu Lifshitz
Jan 6, 2012·Pediatric Emergency Care·Subramanian SenthilkumaranPonniah Thirumalaikolundusubramanian
Nov 27, 2014·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·John Victor PeterJohn L Moran

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