PMID: 15354015Sep 9, 2004Paper

Delayed facial paralysis after vestibular schwannoma surgery: role of herpes viruses reactivation--our experience in eight cases

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Valérie Franco-VidalVincent Darrouzet

Abstract

The objectives of this study were to study the role of herpes virus reactivation in the onset of delayed facial paralysis (DFP) occurring more than 72 hours after vestibular schwannoma (VS) surgery and to advocate specific medical management. We conducted a retrospective case review. University-based, tertiary care center. Eight patients managed for DFP in a series of 348 patients operated for a VS. Patients were evaluated and graded according to the House and Brackmann grading system and followed up for 1 year. A serologic search for specific antiherpes simplex viruses type 1 and 2 (HSV-2) and varicella zoster virus (VZV) antibodies at the onset of DFP and 2 weeks later was possible in three cases. Seven of the eight patients were given intravenous acyclovir (30 mg/kg/ for 5 days) and methylprednisolone (2 mg.kg/ for 7 days). Mean delay of DFP onset was 8.75 days. All treated patients had a House and Brackmann Grade 1 recovery: mean time to recovery was 40.4 days. The last one had only a Grade 3 recovery because he could not be treated because of postoperative transient psychiatric problems. Serologic testing in those patients in whom it could be done revealed either a high level of anti HSV or VZV antibodies at the time of on...Continue Reading

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Citations

Feb 6, 2009·Cochlear Implants International·Shawn Thadathil JosephRupa Aurora
Dec 14, 2011·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Maggie A KuhnPamela C Roehm
Sep 18, 2008·Current Opinion in Otolaryngology & Head and Neck Surgery·Matthew R O'Malley, David S Haynes
Mar 23, 2010·Neurosurgery·Bharat GuthikondaPhilip V Theodosopoulos
Mar 14, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Meghan T TurnerPamela Carol Roehm
Feb 6, 2013·The Laryngoscope·Joshua J ThomColin L W Driscoll
Nov 10, 2018·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·M A AkulovA S Orlova
Nov 8, 2012·Journal of Korean Neurosurgical Society·Jae-Suk HanKwan Park
Sep 2, 2017·Journal of Neurosurgery·Jae Meen LeeSun Ha Paek
May 2, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Sambashivappa BasavarajSabir Kallada
Jul 4, 2008·The Laryngoscope·Derald E BrackmannWilliam H Slattery
Mar 21, 2020·Acta neurochirurgica·Nikhil K MurthyRobert J Spinner
Apr 19, 2007·British Journal of Neurosurgery·H N Simms, L T Dunn
Sep 10, 2015·Neurosurgery·Lucas P CarlstromMichael J Link
Oct 24, 2019·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Alexander L LuryiChristopher A Schutt
Apr 6, 2016·The Journal of Craniofacial Surgery·Zhao HuaLi Shiting

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