Abstract
About 25% of the patients with nonischemic left ventricular (LV) systolic dysfunction improve spontaneously. However, the predictors for functional improvement are not known. We hypothesized that myocardial fibrosis, assessed by cardiac magnetic resonance (CMR) imaging, may predict the reversibility of nonischemic LV systolic dysfunction. CMR was performed in 46 patients. Baseline and follow-up echocardiography was performed to assess the recovery of LV function. There were 24 patients with absence of delayed hyperenhancement (group 1) and 22 patients with delayed hyperenhancement (group 2). There were significant difference for the follow-up LV end-diastolic dimension (56.2 +/- 7.3 versus 62.6 +/- 11.9), LV end-systolic dimension (43.2 +/- 9.2 versus 52.8 +/- 12.6), and LV ejection fraction (LVEF) (46.8 +/- 12.4% versus 31.6 +/- 11.3%). Follow-up echocardiography of 19/24 (79.2%) patients in group 1 showed functional recovery, whereas only 2/22 (9.1%) patient in group 2 showed functional recovery. The absence of delayed hyperenhancement was associated with sensitivity, specificity, positive predictive value, and negative predictive value of 90.5%, 79.2%, 80.0%, and 90.9%, respectively. Absence of delayed hyperenhancement demon...Continue Reading
References
Jan 1, 1991·Japanese Heart Journal·N MaehashiH Fukuzaki
Dec 1, 1987·The American Journal of Cardiology·W C RobertsB M McManus
Mar 1, 1993·American Heart Journal·M TeragakiT Takeda
Dec 15, 1996·Circulation·R J KimR M Judd
Jun 30, 2000·The American Journal of the Medical Sciences·H KhanlouW Forbes
Nov 18, 2000·The New England Journal of Medicine·R J KimR M Judd
Nov 30, 2000·Circulation·F ZannadB Pitt
Sep 6, 2001·Circulation·K M ChoiR M Judd
Nov 3, 2001·Transplant International : Official Journal of the European Society for Organ Transplantation·N de LeeuwJ M Galama
Citations
Jul 27, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Johan VerjansLeonard Hofstra
Nov 4, 2011·European Heart Journal·Darryl P LeongJoseph B Selvanayagam
Feb 2, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Jung Rae ChoSe-Joong Rim
Feb 12, 2014·Texas Heart Institute Journal·Ajit H Goenka, Scott D Flamm
Jul 22, 2008·European Radiology·Frederic MouquetJean Paul Beregi
Dec 25, 2015·Journal of Cardiac Failure·Jeonggeun MoonJong-Won Ha
May 20, 2008·Seminars in Roentgenology·Gisela C Mueller, Anil Attili
May 5, 2007·Cardiology Clinics·James A White, Manesh R Patel
Apr 23, 2009·European Journal of Heart Failure·Eui-Young ChoiNamsik Chung
Apr 6, 2013·Journal of Magnetic Resonance Imaging : JMRI·Manojkumar Saranathan, James Glockner
Nov 3, 2007·Magnetic Resonance Imaging Clinics of North America·James A White, Manesh R Patel
Jul 10, 2013·Journal of Cardiac Failure·Asuka YoshidaKyoichi Mizuno
Feb 19, 2013·International Journal of Cardiology·Keisuke KidaFumihiko Miyake
Dec 29, 2015·Journal of Cardiovascular Electrophysiology·Sandeep PrabhuPeter M Kistler
Sep 12, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Ji Hyun YoonEui-Young Choi
May 17, 2019·Critical Pathways in Cardiology·Osmar Antonio CenturiónLuis Marcelo Miño
Dec 1, 2018·The Journal of Ambulatory Care Management·Richard H Bernstein, Laura A Singh