Skin test reactivity, lymphocyte transformation, and mononuclear cell tissue factor generation were evaluated both before and during systemic anticoagulation in 24 volunteers. Anticoagulation with warfarin decreased skin test induration and tissue factor generation, but lymphocyte trnasformation remained unchanged. An intact coagulation mechanism, including tissue factor generation, appears to be important for the development of skin test induration in humans.
Enhanced procoagulant activity of mononuclear leukocytes in patients with atopic dermatitis and psoriasis
Improved quantitation of delayed-type hypersensitivity responses to sheep erythrocytes in the mouse footpad by estimation of 125I-fibrin deposition
Heparin treatment in patients with human T-lymphotropic virus type I (HTLV-I)-associated myelopathy: a preliminary study
Serum augments the generation of monocyte procoagulant stimulated by bacterial lipopolysaccharide or chemotactic fragments of C5
Characterization of immune responses in different lymphoid compartments during small intestinal allograft rejection
Tissue factor activity in human monocytes is regulated by plasma: implications for the high and low responder phenomenon
Monocytes can be induced by lipopolysaccharide-triggered T lymphocytes to express functional factor VII/VIIa protease activity
Delayed-type hypersensitivity skin reactions in congenital afibrinogenemia lack fibrin deposition and induration
Regulatory roles of T mu and T gamma cells in the collaborative cellular initiation of the extrinsic coagulation pathway by bacterial lipopolysaccharide
A human T cell clone that mediates the monocyte procoagulant response to specific sensitizing antigen
Antigen-induced monocyte procoagulant activity. Requirement for antigen presentation and histocompatibility leukocyte antigen-DR molecules
Suppression of experimental autoimmune diseases and prolongation of allograft survival by treatment of animals with low doses of heparins
Roles for thrombin and fibrin(ogen) in cytokine/chemokine production and macrophage adhesion in vivo.
Legionella pneumophila and related organisms induce the generation of procoagulant activity by peripheral mononuclear cells in vitro
Fibrin in fibroblast cultures--a metabolic study as a contribution to inflammation and tissue repair
Increases of leukocyte tissue factor activity stimulated by red cells sensitized with human blood group alloantibodies
Failure to warfarin to affect the tissue factor activity and the metastatic potential of murine fibrosarcoma cells
Reduced generation of procoagulant activity by endotoxin-stimulated mononuclear cells from patients with chronic myeloid leukaemia
Enhancement of monocyte thromboplastin activity by antigenically stimulated lymphocytes: a link between immune reactivity and blood coagulation
Oral warfarin affects some aspects of systemic immunomodulation with topical dinitrochlorobenzene (DNCB) in rats
Defensin modulates tissue-type plasminogen activator and plasminogen binding to fibrin and endothelial cells.
Treatment with anti-factor VIIa in acute pancreatitis in rats: blocking both coagulation and inflammation?
Identification of an inhibitor of tissue-type plasminogen activator-mediated fibrinolysis in human neutrophils. A role for defensin.
Sensitization of T lymphocytes to thyroid antigen in autoimmune thyroid disease as demonstrated by the monocyte procoagulant activity test
Review article: the pharmacological implications of leucocyte-endothelial cell interactions in Crohn's disease
Monocyte tissue factor induction by activation of beta 2-glycoprotein-I-specific T lymphocytes is associated with thrombosis and fetal loss in patients with antiphospholipid antibodies
Platelet-activating factor modulates endotoxin-induced macrophage procoagulant activity by a protein kinase C-dependent mechanism.
Blood Clotting Disorders
Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.