Delayed magnetic mismatch negativity field, but not auditory M100 response, in specific language impairment.

Neuroreport
Timothy P L RobertsJames Christopher Edgar

Abstract

Recent studies show that electrophysiological markers of auditory processing such as the cortical 100 ms response (M100) and the mismatch field, derived from magnetoencephalography, might be used to identify children with autism spectrum disorders--M100 peak latency--and to stratify children with autism according to the degree of language impairment--mismatch field peak latency. The present study examined the latency of right superior temporal gyrus M100 and mismatch field in a cohort of children and young adolescents with specific language impairment (n=17), in comparison with age-matched and nonverbal intelligence quotient-matched typically developing controls (n=21). Neither group showed symptoms associated with autism. Although M100 latency (reflecting early auditory processing) did not distinguish controls from children with specific language impairment, the later 'change detection' mismatch field response was significantly delayed (by >50 ms) in the specific language impairment group. Linear discriminant analysis confirmed the role of mismatch field latency (92%) but not M100 latency (8%) in distinguishing groups. The present results lend support to the claim that a delayed M100 is specific to autism spectrum disorders (w...Continue Reading

References

Oct 31, 2002·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Dorothy V M Bishop, Courtenay Frazier Norbury
Mar 17, 2005·Neuroreport·Janis E Oram CardyTimothy P L Roberts
Feb 29, 2008·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Janis E Oram CardyTimothy P L Roberts
Nov 10, 2009·Neuroreport·Timothy P L RobertsJ Christopher Edgar
Jan 12, 2010·Autism Research : Official Journal of the International Society for Autism Research·Timothy P L RobertsJ Christopher Edgar
May 21, 2010·Autism : the International Journal of Research and Practice·William FarrHayes Raffle
Mar 12, 2011·Biological Psychiatry·Timothy P L RobertsJ Christopher Edgar

❮ Previous
Next ❯

Citations

Apr 18, 2014·PloS One·Christian KärgelBernhard W Müller
Dec 18, 2013·AJNR. American Journal of Neuroradiology·T P L RobertsJ C Edgar
May 29, 2019·Autism Research : Official Journal of the International Society for Autism Research·Junko MatsuzakiTimothy P L Roberts
Nov 25, 2020·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Zachary J WilliamsTiffany G Woynaroski
Jul 8, 2019·Developmental Neuroscience·Junko MatsuzakiTimothy P L Roberts

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.