Delayed onset of luteinization as a cause of infertility

Fertility and Sterility
P R KoninckxI A Brosens

Abstract

Two groups of infertility patients with regular cycles and apparently normal ovarian function were studied. In group I (n = 28) the infertility could be explained satisfactorily either by tubal occlusion or by infertility of the husband, or the women became pregnant within a few months. In group II (n = 32) no explanation was found for the infertility. Significantly fewer ovulation stigmata were present at laparoscopy in group II than in group I (P less than 0.05). In group I the basal body temperature (BBT) (P less than 0.001) and the plasma progesterone concentrations (P less than 0.05) were significantly elevated on the 1st day following the luteinizing hormone (LH) peak. In group II, THE BBT was slightly elevated on the 1st day following the LH peak (P less than 0.05), but the increase in the plasma progesterone concentrations occurred only on the 2nd day following the LH peak. In four women the onset of the BBT rise followed a normal LH peak with delays respectively, of 3, 4, 4, and 5 days, and in two women no LH peak occurred immediately prior to the onset of the BBT rise. The datings of the endometrial biopsies in these patients were in phase with the onset of the BBT rise but not with the LH peak. It is concluded that a...Continue Reading

Citations

Feb 1, 1987·Clinical Endocrinology·C J HamiltonJ de Haan
Jul 1, 1990·British Journal of Obstetrics and Gynaecology·M P HamiltonC R Whitfield
Mar 1, 1980·British Journal of Obstetrics and Gynaecology·P R KoninckxI A Brosens
Sep 1, 1994·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·P van ZonneveldH P Koppeschaar
Nov 1, 1980·British Journal of Obstetrics and Gynaecology·P R KoninckxI A Brosens
Oct 1, 1982·Clinical Endocrinology·J R CouttsR Fleming
Jun 1, 1993·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·J H CheckW Weiss
Jan 1, 1985·Annals of Clinical Biochemistry·P WoodC Selby
Nov 28, 2020·American Journal of Obstetrics and Gynecology·Roberto Romero
Nov 1, 1993·Prostaglandins, Leukotrienes, and Essential Fatty Acids·A R Priddy, S R Killick

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