PMID: 7023599Sep 1, 1981Paper

Delayed primary wound closure in gangrenous and perforated appendicitis

The British Journal of Surgery
R A Pettigrew

Abstract

A prospective randomized trial was performed on 122 patients with perforated or gangrenous appendicitis to determine whether delayed primary wound closure lowered morbidity from wound infection. The 54 per cent wound infection rate with delayed primary closure was significantly inferior to the 18 per cent infection rate for primary closure with topical ampicillin powder (P = 0.0082), but not significantly different from the 37 per cent infection rate for primary closure alone. Furthermore, patients disliked delayed primary closure, their hospital stay was prolonged and 17 per cent of their wounds became contaminated with Staphylococci before being closed. Delayed primary wound closure should not be used in treating perforated and gangrenous appendicitis wounds.

References

Apr 1, 1977·American Journal of Obstetrics and Gynecology·S E BrownR N Robins
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Citations

Jun 1, 1984·World Journal of Surgery·P R Gaffney
Mar 1, 1993·World Journal of Surgery·W T Morris
Jul 27, 2005·Pediatric Surgery International·Marion C W Henry, R Lawrence Moss
Mar 7, 2007·Pediatric Surgery International·Adnan AslanMustafa Melikoglu
Mar 29, 2002·American Journal of Surgery·Michael HeinzelmannTina Lam
Sep 16, 2014·World Journal of Emergency Surgery : WJES·Boonying SiribumrungwongAmmarin Thakkinstian
May 1, 2012·Journal of the Chinese Medical Association : JCMA·Ruey-An ChiangYao-Chung Tsai
Feb 1, 1990·American Journal of Surgery·J L SecoJ L Santamaria
Mar 7, 2006·Journal of Pediatric Surgery·Sigmund H Ein, Anthony Sandler
Nov 19, 2013·Asian Journal of Surgery·Boonying SiribumrungwongAmmarin Thakkinstian
Sep 27, 2006·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Ruey-An ChiangMing-Jong Bair
Oct 1, 1988·The British Journal of Surgery·Z H KrukowskiN A Matheson
Sep 1, 1982·The British Journal of Surgery·S S BrennanA V Pollock
Jun 1, 1986·The Australian and New Zealand Journal of Surgery·A MacKellar, A J Mackay
Jan 1, 1982·Langenbecks Archiv für Chirurgie·K Schwemmle

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