Delayed reopening of a hemodynamically significant patent foramen ovale after left lung transplantation: emergency management

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
H MalMichel Wolff

Abstract

We report the case of a man who underwent a left-lung transplantation for pulmonary fibrosis and who developed deterioration of his respiratory condition at Day 16 post-operatively, with marked hypoxemia not explained by the usual early respiratory complications of lung transplantation. Contrast-enhanced transthoracic echocardiography identified a patent foramen ovale with massive spontaneous right-to-left shunting. As for the pathogenesis of this right-to-left shunting, we found no evidence supporting an elevation of right-side pressures, with the redirection of the inferior vena cava flow toward the patent foramen ovale being the suspected mechanism. We conclude that delayed reopening of the patent foramen ovale leading to massive right-to-left shunting is a possible complication after lung transplantation.

References

Jan 1, 1997·The Annals of Thoracic Surgery·N C BakrisA C Mehta
Mar 1, 1997·American Journal of Respiratory and Critical Care Medicine·E P Trulock
Oct 6, 1997·The Annals of Thoracic Surgery·F GodartA Wurtz
Apr 8, 1999·The New England Journal of Medicine·S M Arcasoy, R M Kotloff
Jan 8, 2003·Circulation·Bernhard Meier, James E Lock
Feb 26, 2004·The European Respiratory Journal·R M Kotloff, V N Ahya
Dec 6, 2005·International Journal of Cardiology·Carlos J SorianoRafael Paya
Mar 31, 2007·International Journal of Cardiology·Abdenasser DrighilAhmed Bennis
Oct 27, 2007·Annales de cardiologie et d'angéiologie·P AubryA Vahanian
Dec 19, 2007·Clinical Medicine & Research·Ravi K MareeduCharles S McCauley

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Citations

Nov 22, 2011·Revue des maladies respiratoires·C BancalM Bonay
Aug 27, 2014·Revista española de anestesiología y reanimación·J M RabanalM Williams

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