PMID: 7336679Jan 1, 1981Paper

Delayed serum sickness-like transfusion reactions in a multiply transfused patient

Vox Sanguinis
D R Avoy

Abstract

The clinical features and progress of a patient with a fatal myeloproliferative disease are reported. Her care required frequent transfusions of red cell products and components. These transfusions were followed, after varying intervals, by fever, arthralgia, myalgia, headache and pericarditis. These reactions could be avoided by transfusing plasma-free products, and were ameliorated by systemic steroids. This patient, then, is the first reported case of delayed, serum sickness-like transfusion reactions. During the course of her illness she was demonstrated to have antibodies to immunoglobulins. The role of these antibodies, if any, is uncertain.

References

Feb 20, 1978·JAMA : the Journal of the American Medical Association·D Solanki, P R McCurdy
Jan 1, 1966·The Journal of Clinical Investigation·J C Allen, H G Kunkel
Aug 10, 1968·Lancet·G N VyasH H Fudenberg
Dec 1, 1957·Journal of Cellular Physiology. Supplement·F J DIXON

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Citations

Nov 5, 2008·Transfusion·Veroniek SaegemanJan Moerman

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