Delayed surgery after acute traumatic central cord syndrome is associated with reduced mortality

Spine
Andre M SamuelJonathan N Grauer

Abstract

A retrospective study of surgically treated patients with acute traumatic central cord syndrome (ATCCS) from the National Trauma Data Bank Research Data Set. To determine the association of time to surgery, pre-existing comorbidities, and injury severity on mortality and adverse events in surgically treated patients with ATCCS. Although earlier surgery has been shown to be beneficial for other spinal cord injuries, the literature is mixed regarding the appropriate timing of surgery after ATCCS. Traditionally, this older population has been treated with delayed surgery because medical optimization is often indicated preoperatively. Surgically treated patients with ATCCS in the National Trauma Data Bank Research Data Set from 2011 and 2012 were identified. Time to surgery, Charlson Comorbidity Index, and injury severity scores were tested for association with mortality, serious adverse events, and minor adverse events using multivariate logistic regression. A total of 1060 patients with ATCCS met inclusion criteria. After controlling for pre-existing comorbidity and injury severity, delayed surgery was associated with a decreased odds of inpatient mortality (odds ratio = 0.81, P = 0.04), or a 19% decrease in odds of mortality wit...Continue Reading

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Citations

Oct 2, 2015·Neurosurgical Focus·Ethan A WinklerPhiroz E Tarapore
Feb 26, 2016·Clinical Orthopaedics and Related Research·Andre M SamuelJonathan N Grauer
Sep 1, 2016·The Journal of the American Academy of Orthopaedic Surgeons·Daniel D BohlJonathan N Grauer
Jun 17, 2016·The Journal of Bone and Joint Surgery. American Volume·Theodore J Choma, Darrel S Brodke
Apr 4, 2018·The Journal of Bone and Joint Surgery. American Volume·Peter J WagnerMichael P Stauff
Oct 23, 2018·Clinical Spine Surgery : a Spine Publication·Sohaib Z HashmiAlpesh A Patel
Jan 12, 2019·The Journal of Trauma and Acute Care Surgery·Elizabeth Y KillienFrederick P Rivara
May 8, 2018·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Jayne Donovan, Steven Kirshblum
Jun 4, 2019·Global Spine Journal·Srikanth N DiviAlexander R Vaccaro
Mar 25, 2019·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jin-Peng DuDing-Jun Hao
Aug 2, 2019·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·P K Karthik YelamarthyFrancois Theron
Jan 7, 2021·Neurospine·Jutty ParthibanSalman Yousuf Sharif
Jun 12, 2021·Journal of Neurosurgical Sciences·Ryan R PhelpsSanjay S Dhall
Nov 16, 2021·Journal of Neurological Surgery. Part A, Central European Neurosurgery·Gerhard HildebrandtDenis Bratelj

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