Delayed tendon reattachment does not reverse atrophy and fat accumulation of the supraspinatus--an experimental study in rabbits

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Fujio MatsumotoJoachim F Loehr

Abstract

Muscle atrophy and fat accumulation occur after rotator cuff tearing. Whether these changes are reversible after a successful repair is still unknown. Imaging allows only a semi-quantitative assessment of muscle atrophy and fat deposition. As only experimental studies permit a quantification of both, a unilateral detachment and wrapping in a polyvinylidine fluoride membrane of the supraspinatus was done in 22 rabbits. After 12 weeks, the polyvinylidine fluoride membrane was removed in 10 rabbits and the tendon inserted into a bony trough. The opposite shoulder served as control. All rabbits were killed at 24 weeks. Accumulation of fat on the muscle surface as well as between the muscle fascicles and occasionally in the sarcoplasm was increased in both experimental groups when compared to controls (non-reattached 12.8%, reattached 23.5% vs controls 5.4%; all p < 0.005). The muscle atrophy was significant (non-reattached 9.2 ml, reattached 9.1 ml vs controls 10.7 ml; both p < 0.005). Neither atrophy nor fat accumulation were reversed by surgical reattachment of the supraspinatus tendon. On the contrary, the fat accumulation was higher in the reattached group (p < 0.005). The trauma of reattachment, the delay between detachment an...Continue Reading

References

Aug 1, 1989·Acta Orthopaedica Scandinavica·J M Björkenheim
Sep 1, 1994·The American Journal of Sports Medicine·W A GranaR B Reeves
May 1, 1996·Journal of Shoulder and Elbow Surgery·K NakagakiS Tamai
Jan 1, 1996·Journal of Shoulder and Elbow Surgery·A S RokitoF Cuomo
Nov 1, 1996·Journal of Shoulder and Elbow Surgery·J P IannottiG R Williams
Mar 1, 1997·Journal of Shoulder and Elbow Surgery·M KronbergL A Broström
Jul 31, 1999·The Journal of Bone and Joint Surgery. American Volume·A S RokitoJ D Zuckerman
Oct 3, 1999·The Journal of Bone and Joint Surgery. American Volume·C GerberR W Nyffeler
Apr 13, 2000·The Journal of Bone and Joint Surgery. American Volume·C GerberJ Hodler
Oct 21, 2000·The Journal of Bone and Joint Surgery. British Volume·H K UhthoffH Ishii
Apr 1, 1959·Journal of Neurochemistry·M LEESS CARR
May 1, 1992·Journal of Shoulder and Elbow Surgery·L U BiglianiE S Musso

❮ Previous
Next ❯

Citations

Jul 31, 2012·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Sandeep MannavaKatherine R Saul
Mar 30, 2004·Journal of Biomechanics·Jonathan A GimbelLouis J Soslowsky
Feb 24, 2005·Journal of Shoulder and Elbow Surgery·Atsushi YokotaLouis J Soslowsky
Aug 12, 2009·Tissue Engineering. Part B, Reviews·Kathleen A DerwinJesse A McCarron
Aug 23, 2008·The Tohoku Journal of Experimental Medicine·Mitsuyoshi MinetaEiji Itoi
Oct 12, 2010·The Journal of Bone and Joint Surgery. American Volume·Kasra RowshanRanjan Gupta
Jul 2, 2014·Journal of Shoulder and Elbow Surgery·Konstantinos DitsiosAnastasios Christodoulou
Oct 1, 2014·Clinical Orthopaedics and Related Research·Peter L C LapnerGeorge S Athwal
Jan 30, 2015·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Mohit GilotraSyed Ashfaq Hasan
Jan 15, 2013·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Chris Hyunchul Jo, Ji Sun Shin
May 1, 2012·Journal of Shoulder and Elbow Surgery·Jeffrey J BarryC Benjamin Ma
Jan 17, 2012·Journal of Shoulder and Elbow Surgery·Jason R Kang, Ranjan Gupta
May 28, 2003·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Hans K UhthoffKo Himori
Jul 29, 2008·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·L Joseph RubinoLynn A Crosby
Oct 13, 2007·Journal of Shoulder and Elbow Surgery·Christian GerberDominik C Meyer
Jul 1, 2015·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Edward ChoH Mike Kim
Oct 22, 2008·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Eric FreyBruno Fuchs
Jul 20, 2011·Arthritis Care & Research·Salma ChaudhuryScott A Rodeo
Jan 20, 2011·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Yoshiaki ItoigawaEiji Itoi
Mar 20, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·M L KillianL M Galatz
Oct 29, 2011·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Guy TrudelHans K Uhthoff
May 18, 2004·Physical Medicine and Rehabilitation Clinics of North America·Karen P Barr
Jun 28, 2016·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Chris Hyunchul JoJi Sun Shin
Jul 20, 2007·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·L Joseph RubinoLynn A Crosby
Mar 1, 2005·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Dominik C MeyerChristian Gerber
Oct 4, 2016·The Bone & Joint Journal·U ButtI A Trail
Mar 6, 2007·The American Journal of Sports Medicine·Brian R WolfRick W Wright
Dec 3, 2005·The Journal of Bone and Joint Surgery. American Volume·Ori SafranJoseph P Iannotti
Apr 23, 2003·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Hans K UhthoffKo Himori
Aug 12, 2004·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Dominik C MeyerChristian Gerber
Jul 30, 2014·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Hans K UhthoffGuy Trudel
Jan 6, 2010·Clinical Orthopaedics and Related Research·LeAnn M DourteLouis J Soslowsky
Dec 21, 2006·Clinical Orthopaedics and Related Research·Luke S OhRobert G Marx
Mar 11, 2008·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Bruno FuchsC Gerber
Jun 6, 2009·Clinical Orthopaedics and Related Research·Christophe NichBernard Augereau
Jan 26, 2006·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Yoichi KoikeHans K Uhthoff
May 26, 2005·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Yoichi KoikeHans K Uhthoff
Aug 2, 2005·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·L M GalatzS Thomopoulos
Aug 9, 2011·Sports Medicine and Arthroscopy Review·Umile Giuseppe LongoVincenzo Denaro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.