Delayed vasoconstrictor response to venous pooling in the calf is associated with high orthostatic tolerance to LBNP

Journal of Applied Physiology
T HachiyaA P Blaber

Abstract

Central blood volume loss to venous pooling in the lower extremities and vasoconstrictor response are commonly viewed as key factors to distinguish between individuals with high and low tolerance to orthostatic stress. In this study, we analyzed calf vasoconstriction as a function of venous pooling during simulated orthostatic stress. We hypothesized that high orthostatic tolerance (OT) would be associated with greater vasoconstrictor responses to venous pooling compared with low OT. Nineteen participants underwent continuous stepped lower body negative pressure at -10, -20, -30, -40, -50, and -60 mmHg each for 5 min or until exhibiting signs of presyncope. Ten participants completed the lower body negative pressure procedure without presyncope and were categorized with high OT; the remaining nine were categorized as having low OT. Near-infrared spectroscopy measurements of vasoconstriction (Hachiya T, Blaber A, Saito M. Acta Physiologica 193: 117-127, 2008) in calf muscles, along with heart rate (HR) responses for each participant, were evaluated in relation to calf blood volume, estimated by plethysmography. The slopes of this relationship between vasoconstriction and blood volume were not different between the high- and low-...Continue Reading

References

Jan 1, 1991·Journal of Applied Physiology·B D LevineC G Blomqvist
Dec 1, 1987·Journal of Applied Physiology·R G Victor, W N Leimbach
Sep 1, 1986·Journal of Applied Physiology·L K EssandohJ T Shepherd
Dec 1, 1994·Journal of Applied Physiology·D M ManciniJ R Wilson
Apr 1, 1994·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·K M el-Bedawi, R Hainsworth
Jul 1, 1996·Medicine and Science in Sports and Exercise·T AbeT Fukunaga
May 24, 2000·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·C M Brown, R Hainsworth
Aug 24, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·J E GreenleafP Norsk
Jun 19, 2001·American Journal of Physiology. Heart and Circulatory Physiology·V A ImadojemuL I Sinoway
Feb 25, 2003·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·William H Cooke, Victor A Convertino
Mar 1, 2003·Acta Physiologica Scandinavica·T Mano, S Iwase
Jul 1, 1953·The Journal of Physiology·R J WHITNEY
Sep 7, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Julian M StewartLeslie D Montgomery
Oct 18, 2005·Journal of Applied Physiology·Philippe P ArbeilleDania M Mohty

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Citations

Apr 17, 2012·International Journal of Cardiology·Roberto MereuLuciano Bernardi
Jul 1, 2017·Physiological Reports·Alexandre LaurinAndrew Blaber
Dec 13, 2018·Physiological Reviews·Nandu GoswamiVictor A Convertino
Sep 21, 2018·Frontiers in Physiology·Oliver OpatzMartina A Maggioni

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