Delaying ACL reconstruction and treating with exercise therapy alone may alter prognostic factors for 5-year outcome: an exploratory analysis of the KANON trial

British Journal of Sports Medicine
S R FilbayL Stefan Lohmander

Abstract

Identify injury-related, patient-reported and treatment-related prognostic factors for 5-year outcomes in acutely ACL-ruptured individuals managed with early reconstruction plus exercise therapy, exercise therapy plus delayed reconstruction or exercise therapy alone. Exploratory analysis of the Knee Anterior Cruciate Ligament, Nonsurgical versus Surgical Treatment (KANON) trial (ISRCTN84752559). Relationships between prognostic factors (baseline cartilage, meniscus and osteochondral damage, baseline extension deficit, baseline patient-reported outcomes, number of rehabilitation visits, graft/contralateral ACL rupture, non-ACL surgery and ACL treatment strategy) and 5-year Knee Injury and Osteoarthritis Outcome Score (KOOS) pain, symptoms, sport/recreation and quality of life (QOL) scores were explored using multivariable linear regression. Estimates were adjusted for sex, age, body mass index, preinjury activity level, education and smoking. For all participants (n=118), graft/contralateral ACL rupture, non-ACL surgery and worse baseline 36-item Short-Form Mental Component Scores were associated with worse outcomes. Treatment with exercise therapy alone was a prognostic factor forlessknee symptoms compared with early reconstruc...Continue Reading

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Citations

Mar 11, 2018·British Journal of Sports Medicine·Nicholas MohtadiLars Engebretsen
Jun 2, 2018·Orthopaedic Journal of Sports Medicine·Hege GrindemMay Arna Risberg
Apr 19, 2020·BMC Musculoskeletal Disorders·Jackie L WhittakerDavid Otto
Nov 25, 2020·Scandinavian Journal of Medicine & Science in Sports·Michael R KrogsgaardJonathan D Comins
Dec 5, 2020·Scandinavian Journal of Medicine & Science in Sports·Christian Fugl HansenMichael R Krogsgaard
May 6, 2021·Orthopaedic Journal of Sports Medicine·Hanna Tigerstrand GrevnertsJoanna Kvist
May 18, 2021·The Journal of Bone and Joint Surgery. American Volume·Marie PedersenMay Arna Risberg

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Clinical Trials Mentioned

ISRCTN84752559

Software Mentioned

Stata
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