PMID: 2488095Jan 1, 1989Paper

Deleterious effects of intravenous verapamil in Wolff-Parkinson-White patients and atrial fibrillation

Cardiovascular Drugs and Therapy
B StrasbergJ Agmon

Abstract

Three patients presented to the emergency room with atrial fibrillation and fast ventricular response with wide preexcited QRS complexes (Wolff-Parkinson-White syndrome). All three patients received intravenous verapamil (5-10 mg). The first patient developed ventricular fibrillation requiring several defibrillations; the second patient developed severe hemodynamic deterioration requiring urgent cardioversion; in the third patient a marked increment in the ventricular response was noted, however, there was no hemodynamic impairment. Verapamil may cause detrimental results when given to patients with the Wolff-Parkinson-White syndrome and atrial fibrillation. Its administration should therefore be considered as an absolute contraindication in these patients.

Citations

Nov 30, 2000·Current Treatment Options in Cardiovascular Medicine·S Balaji
Aug 28, 2012·Current Treatment Options in Cardiovascular Medicine·Amy N McCammond, Seshadri Balaji
Apr 5, 2003·The Journal of Emergency Medicine·James A NelsonTheodore C Chan
Mar 7, 2009·Chest·Chee W Khoo, Gregory Y H Lip
Nov 2, 2011·Emergency Medicine Clinics of North America·Allan R Mottram, James E Svenson
Sep 12, 2009·Pacing and Clinical Electrophysiology : PACE·Juan ShuGan-Xin Yan

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