Deleterious effects of taurine in cats with digitalis-induced arrhythmias.

European Journal of Pharmacology
J R HintonR A Gillis

Abstract

An established model of digitalis toxicity was used to investigate the antiarrhythmic properties of taurine. I.v. doses of taurine ranging from 0.01 to 4.0 mmole/kg were ineffective in converting a deslanoside-induced arrhythmia to sinus rhythm. Indeed, taurine was found to aggravate the arrhythmia and in three experiments precipitated ventricular fibrillation. In addition, pretreatment with 5 mmole/kg taurine i.v. had no significant effect on the doses of deslanoside to produce ventricular arrhythmia and fibrillation.

References

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Citations

Jul 1, 1995·Journal of Veterinary Internal Medicine·G A KramerP D Pion
Apr 23, 2019·Journal of Geophysical Research. Oceans·L D TalleyJ L Sarmiento
Oct 15, 1976·Biochemical Pharmacology·D S Grosso, R Bressler
Oct 1, 1977·Life Sciences·M F Crass, J B Lombardini

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