Delineating Pro-Angiogenic Myeloid Cells in Cancer Therapy.

International Journal of Molecular Sciences
Benjamin W JohnsonAli S Arbab

Abstract

Recent evidence suggests that myeloid cells are critical in cancer development and therapy resistance processes. Pharmacological targeting of tumor-associated myeloid cells is an emerging approach among upcoming immune therapies. Surprisingly, myeloid cells are heterogeneous, including a subset of the myeloid cell displaying angiogenic properties in solid tumors. There is an urgent need to delineate angiogenic myeloid cell populations in order to facilitate specific targeting of protumor myeloid cells among heterogeneous pool. This review article is intended to compile all the relevant information in the literature for improved understanding of angiogenic myeloid cells and their role in tumor refractoriness to cancer therapy.

References

Oct 12, 2000·Nature Cell Biology·G BergersD Hanahan
Jun 5, 2003·Nature Reviews. Cancer·Gabriele Bergers, Laura E Benjamin
Oct 4, 2005·The Journal of Clinical Investigation·Chunyan XuJohn C Reed
Oct 20, 2006·Cancer Letters·Michael C Schmid, Judith A Varner
Oct 9, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Bernard CummingsBrian O'Sullivan
Apr 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Susanna PurhonenPetri Salven
Jul 11, 2008·Trends in Cell Biology·Farbod ShojaeiNapoleone Ferrara
Mar 19, 2009·Experimental & Molecular Medicine·Shigetomo FukuharaNaoki Mochizuki
Apr 21, 2010·Proceedings of the National Academy of Sciences of the United States of America·G-One AhnJ Martin Brown
Mar 8, 2011·Cell·Douglas Hanahan, Robert A Weinberg
Dec 14, 2011·Genes & Development·Tanaya ShreeJohanna A Joyce
Mar 23, 2012·Nature Reviews. Immunology·Dmitry I GabrilovichVincenzo Bronte
Dec 18, 2013·The British Journal of Radiology·J M Brown
Mar 17, 2015·Trends in Immunology·Lee B Rivera, Gabriele Bergers
Aug 14, 2015·Cancer Research·Russell HughesClaire E Lewis
Apr 5, 2016·OncoTargets and Therapy·Bhagelu R Achyut, Ali S Arbab
Jun 25, 2016·Nature Reviews. Cancer·Camilla EngblomMikael J Pittet
Jul 7, 2016·Nature Communications·Vincenzo BronteDmitry I Gabrilovich
Jan 6, 2017·Cancer Immunology Research·Dmitry I Gabrilovich
Feb 12, 2017·Cell·Juan R Cubillos-RuizLaurie H Glimcher
Apr 11, 2017·The Journal of Clinical Investigation·Yujie HuangJeffrey Greenfield
Jul 15, 2017·Nature Reviews. Cancer·Michele De PalmaTatiana V Petrova
Jan 27, 2018·Cell Death & Disease·Marco B SchaafPatrizia Agostinis
Feb 28, 2018·Cellular Immunology·Mate KissDamya Laoui

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Methods Mentioned

BETA
protein folding
xenograft

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