Delineating the joint hierarchical structure of clinical and personality disorders in an outpatient psychiatric sample

Comprehensive Psychiatry
Miriam K ForbesRobert F Krueger

Abstract

A large body of research has focused on identifying the optimal number of dimensions - or spectra - to model individual differences in psychopathology. Recently, it has become increasingly clear that ostensibly competing models with varying numbers of spectra can be synthesized in empirically derived hierarchical structures. We examined the convergence between top-down (bass-ackwards or sequential principal components analysis) and bottom-up (hierarchical agglomerative cluster analysis) statistical methods for elucidating hierarchies to explicate the joint hierarchical structure of clinical and personality disorders. Analyses examined 24 clinical and personality disorders based on semi-structured clinical interviews in an outpatient psychiatric sample (n=2900). The two methods of hierarchical analysis converged on a three-tier joint hierarchy of psychopathology. At the lowest tier, there were seven spectra - disinhibition, antagonism, core thought disorder, detachment, core internalizing, somatoform, and compulsivity - that emerged in both methods. These spectra were nested under the same three higher-order superspectra in both methods: externalizing, broad thought dysfunction, and broad internalizing. In turn, these three supe...Continue Reading

Citations

May 11, 2018·Journal of Personality Assessment·Thomas A WidigerKatherine M Thomas
May 13, 2020·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Roman KotovUNKNOWN HiTOP Utility Workgroup
Sep 16, 2020·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Irwin D WaldmanJingjing Yang
Sep 20, 2018·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Robert F KruegerJohannes Zimmermann
Apr 25, 2018·Schizophrenia Bulletin·Erik Simonsen, Giles Newton-Howes
Jan 17, 2019·Journal of Personality Disorders·Christopher C ConwayRobert F Krueger
Feb 14, 2021·Journal of Affective Disorders·Holly F Levin-AspensonSara M Stasik-O'Brien
Feb 27, 2021·Journal of Anxiety Disorders·Ivar SnorrasonThröstur Björgvinsson
Nov 14, 2020·The International Journal of Eating Disorders·Melissa J DreierEdward A Selby
Mar 25, 2021·Clinical Psychological Science : a Journal of the Association for Psychological Science·Miriam K ForbesRobert F Krueger
Feb 13, 2021·Annual Review of Clinical Psychology·Roman KotovAidan G C Wright
May 15, 2021·Psychological Medicine·Whitney R RingwaldAidan G C Wright
May 19, 2021·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Robert F KruegerUNKNOWN HiTOP Utility Workgroup
Jul 11, 2021·Scandinavian Journal of Psychology·Lucas de Francisco CarvalhoGiselle Pianowski

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